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The utility of patient-specific surgical plates in free flap mandibular reconstruction: A systematic review and meta-analysis

2025· review· en· W4412490602 on OpenAlexaff
Kainaat Shergill, Arshbir Aulakh, Elana Robibo, Cornelius Kürten, Khanh Linh Tran, Harkaran Singh Dial, Eitan Prisman

Bibliographic record

VenueOral Oncology · 2025
Typereview
Languageen
FieldMedicine
TopicReconstructive Surgery and Microvascular Techniques
Canadian institutionsMcMaster UniversityQueen's UniversityUniversity of British Columbia
Fundersnot available
KeywordsMedicineMeta-analysisStudy heterogeneityMEDLINERandomized controlled trialStandard deviationStatistical significanceConfidence intervalRelative riskDentistrySurgeryOrthodonticsInternal medicineStatisticsMathematics

Abstract

fetched live from OpenAlex

• PSSPs improve mandibular reconstruction accuracy. • Meta-analysis shows reduced intercondylar and intergonial distance deviations. • PSSPs shorten operative time by over an hour in mandibular reconstruction. • PSSPs offer similar complication rates and hospital stay as conventional methods. To evaluate the accuracy and clinical outcomes using patient-specific surgical plates (PSSPs) in mandibular reconstruction. MEDLINE, EMBASE, Scopus, and Web of Science were searched. Study, patient, PSSP characteristics, and clinical outcomes from eligible studies were extracted using a standardized form. The risk of bias was assessed using the Cochrane Risk of Bias tool. Statistical significance for descriptive variables was evaluated using a t -test and chi-square tests. Common and random effects models were used for the meta-analysis. Inter-study heterogeneity was tested using the I 2 test. Our search strategy yielded 1238 records, 12 of which met our eligibility criteria. Overall, the included studies provided a pooled participant size of 585 patients, of which 260 were in the intervention group, and 325 were in the control group. In our meta-analysis, PSSPs were associated with significantly lower intercondylar distance deviation (MD −2.15, 95% CI: −2.81 to −1.49) and intergonial distance deviation (MD −3.62, 95% CI: −6.77 to −0.47). However, the intercondylar angle deviation did not differ between PSSPs and controls. In addition, PSSPs may lead to shorter operative times (MD −77.18 min, 95% CI: −101.99 to −52.36) without significant differences in the length of hospital stay or the rates of postoperative complications. Our results indicate that PSSPs have the potential to improve clinical outcomes in mandibular reconstruction, particularly in reducing operative times and improving reconstruction accuracy. However, moderate-to-high heterogeneity and a high risk of bias underscore the need for further research, especially randomized controlled trials, for a more robust analysis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.621
Threshold uncertainty score0.806

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0120.003
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.362
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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