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Record W4412522232 · doi:10.1038/s41598-025-09444-7

Unlocking the daily impact of parkinson’s challenges through a comprehensive assessment using the ChulaPD ADL questionnaire

2025· article· en· W4412522232 on OpenAlexaboutno aff
Onanong Phokaewvarangkul, Pattamon Panyakaew, Jirada Sringean, Worawit Jankates, Saisamorn Phumphid, Chanawat Anan, Kanyawat Sanyawut, Roongroj Bhidayasiri

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsnot available
FundersThailand Science Research and InnovationNational Research Council of ThailandChulalongkorn University
KeywordsActivities of daily livingPhysical therapyMedicineParkinson's diseaseCohortMontreal Cognitive AssessmentPhysical medicine and rehabilitationGrading (engineering)DiseasePsychologyCognitive impairmentInternal medicine

Abstract

fetched live from OpenAlex

The ChulaPD ADL questionnaire is a meticulously developed tool by experts in Parkinson's disease (PD) and movement disorders, designed to assess functional limitations in daily activities. It comprehensively evaluates 15 key aspects of daily life through 115 items, including 15 for grading limitations and 100 for ADL limitations. Validated in a pilot study with 30 PD participants, the questionnaire demonstrated strong reliability. In a larger cohort of 231 PD patients, it showed moderate to high correlations with age, Hoehn and Yahr score, levodopa equivalent dose, Montreal Cognitive Assessment, and various UPDRS scores, highlighting its effectiveness in capturing disease-related changes. A grading limitation threshold of 13 points or above was particularly effective in identifying postural instability, achieving 81.4% sensitivity and 50.7% specificity, with an area under the curve (AUC) of 0.747. This underscores its utility in reflecting disease progression and its impact on daily functions. The ChulaPD ADL questionnaire is a relevant, reliable, and valid tool for assessing activities of daily living in patients with PD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.049
GPT teacher head0.366
Teacher spread0.317 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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