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Record W4412582462 · doi:10.3389/fneur.2025.1621265

Development of the Common Cognitive Complaints after Concussion (C4) questionnaire: a treatment-planning tool for military service members and veterans with mild traumatic brain injury

2025· article· en· W4412582462 on OpenAlexaff
Lisa H. Lu, Glenn Curtiss, Douglas B. Cooper, Amy O. Bowles, Melissa R. Ray, Martha LeBlanc, Blessen C. Eapen, Robert D. Shura, Lyn S. Turkstra

Bibliographic record

VenueFrontiers in Neurology · 2025
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsMcMaster University
FundersCongressionally Directed Medical Research ProgramsNIH Clinical CenterU.S. Department of Veterans Affairs
KeywordsConcussionTraumatic brain injuryRehabilitationCognitionPost-concussion syndromePsychologyPhysical therapyMedicineClinical psychologyPhysical medicine and rehabilitationPoison controlInjury preventionPsychiatryMedical emergency

Abstract

fetched live from OpenAlex

Objective: To develop an activity-focused self-report tool to guide selection of treatment targets in cognitive rehabilitation for adults with mild traumatic brain injury (mTBI). Setting: Military and veteran treatment facilities. Participants: Twenty-one service members and 32 veterans with a history of mTBI; 25 veterans with orthopedic injury (OI). Design: Clinical tool development. Main measures: Common Cognitive Complaints after Concussion (C4) questionnaire. Results: We reviewed measures used in mTBI research or clinic, to identify items that could be used for selecting activity-level therapy targets as part of a treatment planning tool. To establish face and content validity, an initial item pool was reviewed by five speech-language pathology or occupational therapy mTBI experts who selected items relevant to their clinical practice, gave feedback on item wording, and suggested additional items. The result was a questionnaire with 22 activity-based items and one bias-check item. The C4 was then used in a feasibility mTBI treatment trial to identify treatment targets, and clinicians provided feedback on its utility. The C4 was also administered to an OI group to evaluate the distinctiveness of the items to mTBI symptoms. Conclusion: The C4 adequately captured activity-level functional impairments common to mTBI, and clinicians endorsed its utility as a useful tool to personalize treatment targets.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.007
Threshold uncertainty score0.037

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.023
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.335
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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