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Record W4412594859 · doi:10.1016/j.jad.2025.119950

Psychological distress and vulnerability: Contrasting associations with cognitive performances based on sex and cardiovascular health

2025· article· en· W4412594859 on OpenAlexafffund
Marie Payer, Emma Gabrielle Dupuy, Florent Besnier, Thomas Vincent, Christine Gagnon, Marie-France Marin, Louis Bherer

Bibliographic record

VenueJournal of Affective Disorders · 2025
Typearticle
Languageen
FieldPsychology
TopicCOVID-19 and Mental Health
Canadian institutionsUniversité de MontréalMontreal Heart InstituteInstitut Universitaire en Santé Mentale de QuébecInstitut Universitaire de Gériatrie de MontréalUniversité du Québec à Montréal
FundersFonds de Recherche du Québec - SantéFondation Mirella et Lino SaputoFondation Institut de Cardiologie de MontréalUniversité de Montréal
KeywordsAnxietyClinical psychologyLonelinessCognitionPsychologyDistressRuminationDepression (economics)StressorPsychiatry

Abstract

fetched live from OpenAlex

The COVID-19 pandemic has impacted individuals diversely, leading to psychological distress, loneliness and subjective cognitive complaints. People with chronic medical conditions such as cardiovascular diseases (CVD) and those with psychological vulnerabilities were at greater risk of experiencing severe psychological consequences. Women have also reported higher levels of vulnerability and anxiety symptoms compared to men, although this difference appears to lessen with age. This combination of medical conditions, symptoms, and psychological vulnerabilities may influence cognitive aging. Using the COVID-19 pandemic as a universal stressor, this study examines how this combination relates to cognitive health in men and women aged 50 years and over. A total of 122 individuals with stable CVD (87 men, 71.3 %) and 127 healthy individuals (30 men, 23,6 %) completed neuropsychological assessments and questionnaires assessing psychological distress (stress, depression, anxiety symptoms) and psychological vulnerabilities (anxiety sensitivity, rumination, intolerance of uncertainty, and anxious traits). Among healthy participants, men with higher psychological vulnerabilities showed lower global cognitive performance (B = -2.097, p = .002) compared to their female counterparts (B = 0.022, p = .946). Lower psychological distress was associated with better executive functioning performance in individuals with CVD (B = -0.218, p = .019). These findings show evidence that among individuals over 50, psychological distress and vulnerabilities can be associated with lower cognitive performances in executive functioning and global cognitive performance respectively. However, these associations differ according to medical conditions and sex where higher psychological vulnerability among healthy men may act as a risk factor for lower global cognitive health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.389
Teacher spread0.365 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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