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Record W4412636306 · doi:10.1002/jeo2.70357

Isolated tibial deformity is the most prevalent varus pattern in North American patients undergoing medial opening wedge high tibial osteotomy

2025· article· en· W4412636306 on OpenAlex
Takaaki Hiranaka, Takeo Tokura, Nicola D. Mackay, Ryan M. Degen, Kevin Willits, Robert Litchfield, Alan Getgood

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Experimental Orthopaedics · 2025
Typearticle
Languageen
FieldMedicine
TopicTotal Knee Arthroplasty Outcomes
Canadian institutionsFowler Kennedy Sport Medicine Clinic
Fundersnot available
KeywordsMedicineHigh tibial osteotomyVarus deformityDeformityOsteotomyOrthopedic surgerySurgeryTibiaLog-rank testOrthodonticsSurvival analysisOsteoarthritis

Abstract

fetched live from OpenAlex

Abstract Purpose To evaluate the location of deformity in varus alignment in a North American population and assess early total knee arthroplasty (TKA) conversion rates and TKA‐free survival following medial opening wedge high tibial osteotomy (MOWHTO) based on the bony deformity location. Methods A retrospective analysis was performed on patients with varus alignment who underwent MOWHTO. Deformity analysis measured the hip–knee–ankle (HKA) angle, mechanical medial proximal tibial angle (mMPTA) and mechanical lateral distal femoral angle (mLDFA) using automated software. An abnormal mMPTA was defined as <85° and an abnormal mLDFA was defined as >90°. Cases were classified into four groups based on deformity location: tibial, femoral, combined or no bony deformity. The differences in TKA conversion rates among groups were analysed using the chi‐square test, while TKA‐free survival was determined using Kaplan–Meier survival analysis, with between‐group differences assessed using the log‐rank test. Results A total of 271 patients were included (mean age: 51.6 years; mean follow‐up: 3.6 years). The mean HKA angle was 173.0° ± 3.1°. Among the 271 patients, 38% ( n = 103), 18% ( n = 48), 11% ( n = 30) and 33% ( n = 90) had tibial, femoral, combined and no bony deformity, respectively. TKA conversion rates were 3% ( n = 3/103), 0% ( n = 0/48), 7% ( n = 2/30) and 9% ( n = 8/90) for the tibial, femoral, combined and no bony deformity groups, respectively, with no significant difference among the groups ( p = 0.080). Kaplan–Meier survival analysis showed no significant difference in TKA‐free survival among the four groups ( p = 0.185). Conclusion In this North American cohort, various varus deformity locations were analysed, with isolated tibial deformity being the most prevalent. Regardless of deformity location, TKA conversion rates remained low, suggesting that MOWHTO may be beneficial even in patients without isolated tibial deformity. Level of Evidence Level III.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.022
Threshold uncertainty score0.972

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.272
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it