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Record W4412651529 · doi:10.1101/2025.07.24.25332091

The Need for Developing Consensus-Based Guidelines in Assessing Parkinson’s Disease Laterality

2025· preprint· en· W4412651529 on OpenAlexaff
Emily Houston, Vivikta Iyer, James T. Boyd, Deepak Gupta

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsCentre for Movement Disorders
Fundersnot available
KeywordsLateralityDiseasePsychologyMedicineNeurosciencePathology

Abstract

fetched live from OpenAlex

Abstract This study investigated the correlation between Parkinson’s disease laterality, as defined by the Hoehn and Yahr (HY) scale, and appendicular parkinsonism scores from the MDS-UPDRS Part III using the PPMI dataset. While most cases (89.6%) showed congruence, a 10.4% discordance suggests that factors beyond appendicular parkinsonism influence clinical HY staging, highlighting a need for standardized guidelines.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.265
metaresearch head score (Gemma)0.447
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.265
Threshold uncertainty score0.906

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2650.447
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0050.003
Science and technology studies0.0020.002
Scholarly communication0.0100.007
Open science0.0070.006
Research integrity0.0040.006
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.081
GPT teacher head0.381
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

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