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Record W4412707522 · doi:10.1016/j.jcjo.2025.07.002

Choroidal features on widefield optical coherence tomography angiography in eyes with circumscribed choroidal hemangioma

2025· article· en· W4412707522 on OpenAlexvenueno aff
Judith Kreminger, Reinhard Told, Stephanie Rokitansky, Adrian Reumueller, Roman Dunavoelgyi

Bibliographic record

VenueCanadian Journal of Ophthalmology · 2025
Typearticle
Languageen
FieldMedicine
TopicOcular Oncology and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineVascularityOphthalmologyOptical coherence tomography angiographyNuclear medicineOptical coherence tomographyRadiology

Abstract

fetched live from OpenAlex

OBJECTIVE: To evaluate choroidal morphologic and vascular findings in eyes with circumscribed choroidal hemangioma (CCH) in a 21 mm × 26 mm widefield (WF) OCT-Angiography (OCTA; VG200D: Intalight Inc., San Jose, CA). METHODS: Consecutive patients with CCH were included in this prospective, observational study at the Department of Ophthalmology and Optometry, Medical University of Vienna, Austria. Imaging consisted of ultrasonography and WF-OCTA. Choroidal vascularity index (CVI) and choroidal thickness (CT) were assessed in study eyes (SE) and fellow eyes (FE) using the software of the device. Measurement of CT and CVI excluded the area of CCH and an equivalent area of FE. RESULTS: Nineteen patients (female: n = 9 (47.4%), mean age: 61 ± 11 years) were included in the study. In ultrasonography, the mean largest basal diameter and thickness were 7.32 ± 2.12 mm and 2.81 ± 0.75 mm, respectively. CT was statistically significantly higher in SE, as compared to FE (294.6 ± 74.2 µm vs 239.9 ± 46.8 µm; paired t test p < 0.001), while CVI was statistically significantly lower in SE, as compared to FE (0.44 ± 0.05 vs 0.45 ± 0.05; paired t test: p = 0.012). Intraretinal or subretinal fluid had no statistically significant influence on CT (with fluid: 303.0 ± 84.3 µm vs without fluid: 285.3 ± 65.0 µm; t test: p = 0.619) and CVI (with fluid: 0.42 ± 0.05 vs without fluid: 0.45 ± 0.03; t test: p = 0.185). CONCLUSIONS: Intraretinal or subretinal fluid had no impact on CT and CVI of SE. CT is higher and CVI is lower in SE as compared to FE, when excluding the area of CCH in SE and an equivalent area in FE. This suggests that the choroid plays a crucial role in the disease mechanism of CCH.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.021

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0030.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.276
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractno

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