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Proteus Project - CRISPR-Based Programmable Therapeutics for Targeted Apoptosis in Cancer Cells

2025· preprint· en· 0 citations· W4412731360 on OpenAlex· 10.21203/rs.3.rs-7160959/v1

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

CRISPR-based cancer therapeutic preprint; a biomedical engineering question.

GPT-5.6 (high)OUT
genre: other
about Canada: no
confidence: high

The title indicates a biomedical CRISPR therapeutic project rather than a study of research.

Grok 4.5OUT
genre: other
about Canada: no
confidence: high

CRISPR therapeutic engineering for cancer; domain biotech title with empty abstract.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Research Square
Topic
CRISPR and Genetic Engineering
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
McGill University
Funders
Keywords
CRISPRApoptosisCancer researchTargeted therapyCancerPumaProteusComputational biologyChemistryBiologyGeneticsGene
Has abstract in OpenAlex
no