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Record W4412741518 · doi:10.1093/jnci/djaf199

Re-envisioning the value proposition for investment in cancer care

2025· article· en· W4412741518 on OpenAlexaff
Beverley M. Essue, Adrian Gheorghe, Gary Rodin, Richard Sullivan

Bibliographic record

VenueJNCI Journal of the National Cancer Institute · 2025
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsPrincess Margaret Cancer CentreInstitute for Work & HealthInstitute of Health Services and Policy ResearchUniversity of Toronto
FundersWorld Bank GroupMedical Research CouncilGlobal Alliance for Chronic Diseases
KeywordsBusinessHealth careEquity (law)Value propositionRisk analysis (engineering)Economic growthPublic economicsEconomicsPolitical scienceMarketing

Abstract

fetched live from OpenAlex

The place of cancer within broader health system development highlights key contradictions and distortions. Although innovation in cancer care, spanning medicines, artificial intelligence, and radiation therapy, are advancing rapidly, these technologies can be costly and often provide marginal benefits. Lower-cost approaches, such as screening, patient navigation, and supportive care, remain underutilized, especially in developing health systems. Simultaneously, the financial burden of cancer exacerbates inequities, driving patients into poverty and straining under-resourced systems. To address these contradictions, we call for a re-envisioning of cancer care as a strategic investment within health systems by presenting 4 key transitions: (1) a shift in the predominant narrative of cancer control as a clinical problem to positioning it as a universal health system priority, with far-reaching societal and economic benefits; (2) a greater emphasis on how cancer care supports health system strengthening across the full continuum of services involved in cancer control; (3) a view on cancer treatment as a gateway for technology and systemic investments, showcasing the potential to generate and use cross-cutting improvements with benefits across clinical areas; and (4) the need to align cancer control with rigorous fiscal, economic, and operational planning to ensure that investments deliver broad and sustainable health system impacts. By embedding cancer control into health system development, governments can optimize resources, strengthen system resilience and close equity gaps while addressing current and future health challenges.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.035
metaresearch head score (Gemma)0.045
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.035
Threshold uncertainty score0.184

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0350.045
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0030.019
Scholarly communication0.0180.018
Open science0.0020.008
Research integrity0.0040.012
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.363
GPT teacher head0.500
Teacher spread0.137 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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