Correlation of Point‐of‐Care Intestinal Ultrasound With Endoscopic Disease Severity in Crohn's Disease
Bibliographic record
Abstract
Background: Intestinal ultrasound is increasingly being used in the management of patients with inflammatory bowel disease (IBD). We aim to evaluate the accuracy of intestinal ultrasound in a point-of-care setting in India and compare it with ileo-colonoscopy, the current gold standard. Methods: In this prospective observational study, consecutive patients with a diagnosis of Crohn's disease seen at initial presentation or follow-up were included. At the out-patient visit, clinical severity and biomarkers were documented, and point-of-care intestinal ultrasound was performed. Colonoscopy was performed within 1 week for all patients. Results: A total of 254 patients with Crohn's disease who underwent ileo-colonoscopy were included in the study. The mean bowel wall thickness (BWT) in patients with normal endoscopy (SES-CD < 2) was 2.09 mm. The mean BWT in patients with mild, moderate to severe, and severe disease activity was 4.7, 5.23, and 6.25 mm, respectively. A threshold of 3.4 mm had the best ability to predict the presence of endoscopic disease activity, with a sensitivity of 93%, specificity of 90%, and AUC of 0.96 in this study. The presence of color Doppler signals had a sensitivity of 96.3% and specificity of 91.2% to predict the presence of endoscopic disease activity. Inflammatory fat and bowel wall stratification (BWS) had a higher odds ratio to predict more severe disease. Conclusion: Point-of-care-intestinal ultrasound has good correlation with ileocolonoscopy and can be utilized to assess and monitor disease activity, which should facilitate real-time decision making in the management of patients with IBD.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".