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Record W4412828751 · doi:10.2215/cjn.0000000796

A Qualitative Study Describing the Perspectives on Frailty and Its Management in Individuals with Kidney Failure

2025· article· en· W4412828751 on OpenAlexafffundabout
Stephanie Thompson, Joanna Czupryn, Rachelle Davies, Clara Bohm, Marcello Tonelli, Jennifer M. MacRae, Karthik Tennankore, Carmel Montgomery, Sara N. Davison

Bibliographic record

VenueClinical Journal of the American Society of Nephrology · 2025
Typearticle
Languageen
FieldMedicine
TopicFrailty in Older Adults
Canadian institutionsDalhousie UniversitySeven Oaks General HospitalUniversity of CalgaryUniversity of Alberta
FundersAmgen Canada
KeywordsMedicinePsychological interventionThematic analysisQualitative researchGerontologyMEDLINEDialysisMultidisciplinary approachFamily medicineNursingInternal medicine

Abstract

fetched live from OpenAlex

Key Points The term, frailty, had unclear meaning for most participants but was commonly explained as weakness, dependence, and unmodifiable. Knowledge of frailty assessment tools and the evidence to support their prognostic utility was low among clinicians. Though patients and caregivers saw value in discussing frailty, the label of frailty was often viewed as pejorative. Background Frailty is highly prevalent among individuals with kidney failure and independently associated with poor health outcomes. Identifying and managing frailty can inform prognosis and care but stakeholders' understanding of frailty and their perspectives on how to detect and manage it in routine kidney care are unknown. Methods We recruited participants from four Canadian kidney programs in Alberta, Manitoba, and Nova Scotia from January 2021 to June 2023. We conducted focus groups and semistructured interviews with patients (50 years or older with dialysis-dependent or nondependent kidney failure), caregivers, allied health care professionals, and nephrologists. We used qualitative description and inductive thematic analysis to describe their perspectives. Results Ninety-one people participated: patients ( N =31), caregivers ( N =8), kidney allied health care professionals ( N =38), and nephrologists ( N =14). We identified three themes, each with subthemes: ( 1 ) What is frailty? All groups expressed uncertainty, but frailty was commonly described as physical, visible, inevitable, and fixed; ( 2 ) discussing frailty: the value of knowing what to expect with frailty, and frailty as a difficult topic to discuss; ( 3 ) frailty assessment and management: skepticism from patients and caregivers that frailty is measurable; support from clinicians for a systematic approach to identifying frailty but a lack of knowledge on multidisciplinary roles and potential interventions. For all groups, having actionable solutions after identifying frailty was key for acceptability and successful implementation. Conclusions Education on the nature and potentially modifiable aspects of frailty as well as the scope and potential benefits of frailty interventions is necessary for successful implementation of frailty detection and management in kidney care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.071
Threshold uncertainty score0.142

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0200.025
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0180.014
Scholarly communication0.0040.004
Open science0.0020.006
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.423
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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