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Record W4412834663 · doi:10.1093/haschl/qxaf151

A policy roadmap for sustainable mass-testing

2025· article· en· W4412834663 on OpenAlexaff
Sergey N. Krylov, Svetlana M. Krylova, An T. H. Le, Seyed M. Moghadas, Amin Mawani, Nima Tabatabaei, Manos Papagelis, Peter Tsasis, Mary Wiktorowicz, R. Shayna Rosenbaum

Bibliographic record

VenueHealth Affairs Scholar · 2025
Typearticle
Languageen
FieldMedicine
TopicSARS-CoV-2 detection and testing
Canadian institutionsBaycrest HospitalCentre for Global Health ResearchYork University
Fundersnot available
KeywordsBusinessInvestment (military)PandemicRisk analysis (engineering)Benchmark (surveying)Environmental economicsCoronavirus disease 2019 (COVID-19)EconomicsMedicine

Abstract

fetched live from OpenAlex

Population-wide mass testing with affordable self-tests can drastically reduce lives lost and minimize economic and societal costs during pandemics, especially if deployed before vaccines. During COVID-19, however, the development of self-test manufacturing and distribution capacity lagged behind vaccine rollout and was dismantled once surges subsided, returning us to a prepandemic state. As no new capacity has since been secured, future mass-testing would again face costly delays. To mitigate this risk, we propose a policy roadmap for an economically viable mass-testing system that can be sustained between crises and rapidly scaled during emergencies. Public investment in R&D to improve the sensitivity of affordable self-tests-not to achieve a single benchmark, but to advance point-of-need technologies across medical and nonmedical applications-is essential. Improved sensitivity would enable new uses in routine health screening, food safety, and environmental monitoring, generating steady demand and production capacity that can expand as needed. This demand would support a robust system anchored by four mutually reinforcing pillars: scalable manufacturing, real-time data infrastructure, predictive analytics, and sustainable financing. Prioritizing sensitivity can transform mass testing from a reactive measure into a durable public health foundation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.010
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.767
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.010
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.371
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2025
Admission routes1
Has abstractyes

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