Effects of combining increased lysine (protein) supply in late gestation and domperidone in lactation on sow and piglet performances
Bibliographic record
Abstract
The aim of this project was to determine the impact of either increasing standardized ileal digestible (SID) Lys intake by 40% in gilts from days 85 to 111 of gestation, or combining that treatment with an increase in prolactin concentrations during lactation, on sow and piglet performances. On day 85 of gestation gilts were divided in three groups: (1) fed SID Lys at estimated NRC requirement (CTL, control, n = 23) until day 111 of gestation, (2) fed SID Lys at 40% above requirement via additional soybean meal (LYS, n = 22) until day 111 of gestation, or (3) fed SID Lys at 40% above requirement via additional soybean meal (LYSDOMP, n = 21) until day 111 of gestation and receiving domperidone throughout lactation. Experimental diets were isoenergetic. The LYSDOMP sows were injected daily with the dopamine receptor antagonist domperidone (0.5 mg/kg body weight, BW) from the day after farrowing until weaning. Additionally, they were fed 0.5 mg/kg BW of domperidone twice daily for the first 4 d of lactation. The CTL and LYS sows received injections and per os treatment with the vehicle. Litter size was standardized to 12 ± 1, and piglets were weighed on days 1, 7, and 22. Sow feed intake was recorded daily. Blood samples were collected on days 84 and 110 of gestation and days 1, 7, and 21 of lactation to measure prolactin, IGF-I, urea, free fatty acids (FFA), glucose (gestation only), and amino acids (gestation only). Milk samples were obtained on day 7 of lactation. Sow BW and backfat thickness throughout the study and feed intake in lactation were not affected by treatments (P > 0.10). Prolactin concentrations were greater for LYSDOMP compared with CTL and LYS sows on days 7 and 21 (P < 0.0001). Treatments did not alter IGF-I, glucose, or FFA concentrations at any time (P > 0.05), and urea was greater in LYS and LYSDOMP than CTL sows on day 110 of gestation (P < 0.05). Estimated milk yield or piglet growth rate was not affected by treatments (P > 0.10). In conclusion, feeding supplementary Lys (protein) in late gestation, either with or without domperidone in lactation, did not increase sow milk yield. Findings emphasize that a greater litter size was likely needed to see beneficial effects of supplementary Lys, and that the use of primiparous sows or inadequate lactational feed intake may have impeded the effects of the domperidone.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".