MétaCan
Menu
Back to cohort
Record W4412885349 · doi:10.1002/mdc3.70265

Split‐Belt Treadmill for Falls, Gait Asymmetry, and Freezing in Parkinson's Disease

2025· article· en· W4412885349 on OpenAlexafffund
Sanskriti Sasikumar, Gianluca Sorrento, Anthony E. Lang, Antonio P. Strafella, Alfonso Fasano

Bibliographic record

VenueMovement Disorders Clinical Practice · 2025
Typearticle
Languageen
FieldHealth Professions
TopicBalance, Gait, and Falls Prevention
Canadian institutionsOntario Brain InstituteCentre for Addiction and Mental HealthMental Health Research CanadaToronto Western HospitalUniversity of Toronto
FundersCanadian Institutes of Health Research
KeywordsCadencePhysical medicine and rehabilitationGaitMedicineGait trainingTreadmillPhysical therapyBalance (ability)RehabilitationParkinson's diseaseSTRIDEDiseaseInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Individuals with Parkinson's disease (PD) can adapt to new gait patterns on a split-belt treadmill (SBTM), a tool previously used to rehabilitate gait asymmetry because of stroke. OBJECTIVES: The goal was to determine whether SBTM rehabilitation is superior to conventional "tied" treadmill (TM) in reducing falls, freezing of gait (FOG), and improving gait asymmetry. METHODS: Twenty-eight participants with idiopathic PD and treatment-resistant FOG underwent 18 sessions of SBTM and TM training. Primary outcome was the incidence of falls 3 months after training, and secondary measures included spatiotemporal gait variables (treadmill and over-ground), motor scores, and performance on FOG and balance questionnaires. RESULTS: Treadmill training improved falls regardless of intervention (SBTM: P < 0.05; TM: P < 0.01), although benefits were not sustained at 3 months. SBTM did not meet the a priori 20% superiority threshold for falls prevention. Asymmetry index, temporal asymmetry, and stance time (P ≤ 0.01 in both groups) reduced after training. Swing time increased after training with both interventions (P ≤ 0.01). FOG and ABC scores also improved (P ≤ 0.01 in both groups), however, these improvements were not sustained at 3 months. Cadence and over-ground asymmetry index improved with both interventions (P ≤ 0.01), although only reduced cadence was sustained at 3 months (P = 0.05). Other over-ground parameters including gait velocity, stride length, double-support time improved with TM training only. CONCLUSIONS: SBTM was not superior to TM training in improving incidence of falls. Both interventions improved FOG and spatiotemporal gait parameters, although TM training translated better to over-ground walking.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.008
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.392
Threshold uncertainty score0.956

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.445
Teacher spread0.403 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueMovement Disorders Clinical PracticeSame topicBalance, Gait, and Falls PreventionFrench-language works237,207