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Record W4412928695 · doi:10.1111/echo.70255

The Role of Right Ventricular Embryology in Echocardiographic Assessment of RV Function

2025· review· en· W4412928695 on OpenAlexaff
Ghassan Al-Naami

Bibliographic record

VenueEchocardiography · 2025
Typereview
Languageen
FieldMedicine
TopicCongenital Heart Disease Studies
Canadian institutionsAlberta Medical Association
Fundersnot available
KeywordsVentricleCardiologyEmbryologyInternal medicineMedicineHeart diseaseDoppler imagingVentricular functionAnatomyDiastole

Abstract

fetched live from OpenAlex

The right ventricle (RV) possesses a complex geometry and unique functional characteristics stemming from its embryologic development. Unlike the left ventricle (LV), which arises primarily from the primary heart field, the RV originates predominantly from the anterior or secondary heart field, influencing its structural organization, myocardial fiber orientation, and contractile patterns. This embryologic origin is not only essential for understanding congenital anomalies but also profoundly impacts the interpretation and accuracy of echocardiographic modalities used to assess RV function. This review explores how knowledge of RV embryology enhances the clinical application of echocardiographic methods, including tricuspid annular plane systolic excursion (TAPSE), tissue Doppler imaging (TDI), RV fractional area change (FAC), 3D echocardiography, and RV longitudinal strain. Incorporating embryologic insights provides a more anatomically and physiologically grounded approach to evaluating RV performance, especially in congenital heart disease and right heart failure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.937
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.005
Bibliometrics0.0030.005
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.308
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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