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Mutagenesis and production of double-flowered gentians via regeneration from ion beam-irradiated leaves

2025· article· en· W4412963795 on OpenAlexfundno aff
Masahiro Nishihara, Akiko Hirabuchi, Akira Abe, Motoki Shimizu, Fumina Goto, Chiharu Yoshida, Takashi Shimokawa, Suguru Ozawa, Zenbi Naito, Keiichiro Nemoto

Bibliographic record

VenuePlant Biotechnology · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Genetic and Mutation Studies
Canadian institutionsnot available
FundersInstitute of GeneticsBio-oriented Technology Research Advancement Institution
KeywordsBiologyRegeneration (biology)MutagenesisIrradiationProduction (economics)Ion beamBotanyCell biologyBeam (structure)GeneticsMutationGeneOpticsNuclear physicsPhysics

Abstract

fetched live from OpenAlex

Gentians are important ornamental plants, and gentian cultivars have been actively bred for decades. However, limited genetic resources are currently available for breeding; therefore, artificial mutagenesis has been applied to generate mutants. In this study, we developed a simple and efficient regeneration-mediated method for ion beam mutagenesis in the Japanese gentian hybrid cultivar ‘Albireo’ (Gentiana scabra × G. triflora). Carbon and neon ion species were tested. Effect of ion beam irradiation on callus formation from leaves was initially evaluated. Tissue culture was then continued, adventitious shoots were induced from calli, and many regenerated plants were obtained. These plants were cultivated until flowering, and two cultivated lines exhibiting a double-flowered phenotype were identified from leaves exposed to 9 and 12 Gy of neon ion beam irradiation among approximately 200 individuals. We analyzed one line derived from irradiation with 9 Gy of neon ions, named Ne9Gy#34, in detail. The agamous gene (AG1), previously identified as the gene responsible for the double-flower phenotype in gentians, was not amplified in the G. scabra allele by genomic polymerase chain reaction. Moreover, next-generation sequencing also indicated that the reads were mapped to the genomic region of the G. triflora AG1 but not to that of G. scabra, suggesting that the deletion of G. scabra AG1 led to the double-flowered phenotype. Ne9Gy#34 also exhibited increased flower size, suggesting additional mutations in genes other than AG1. In summary, the developed regeneration-mediated method represents a promising approach for inducing gentian mutagenesis and efficiently producing novel traits in this plant.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.168

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.199
Teacher spread0.186 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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