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Record W4412988866 · doi:10.1371/journal.pone.0328845

How do the neurocognitive profiles of FASD and complex trauma compare in the pediatric population?: A scoping review protocol

2025· review· en· W4412988866 on OpenAlexaff
Rishi Gupta, Colleen Pawliuk, Denise Somuah-Asamoah, Katelynn E. Boerner, Jennifer Engle, Sarah M. Hutchison, Gurpreet Dhaliwal

Bibliographic record

VenuePLoS ONE · 2025
Typereview
Languageen
FieldMedicine
TopicPrenatal Substance Exposure Effects
Canadian institutionsSunny Hill Health Centre for ChildrenUniversity of British Columbia
Fundersnot available
KeywordsNeurocognitivePsycINFOMedicineClinical psychologyMEDLINEPopulationContext (archaeology)CognitionPsychiatryPsychology

Abstract

fetched live from OpenAlex

OBJECTIVE: The aim of this scoping review is to compare the neurocognitive profiles of children and youth diagnosed with Fetal Alcohol Spectrum Disorder (FASD) to those of children and youth diagnosed with complex trauma. INTRODUCTION: The neurocognitive challenges resulting from prenatal alcohol exposure (PAE) have been defined by the FASD diagnosis. Complex trauma exposure, in the form of adverse childhood experiences (ACEs), is associated with similar neurocognitive deficits. Recent evidence suggests ACE exposures to be higher in individuals with FASD as compared to non-FASD controls which warrants a closer look at the overlap between the neurocognitive deficits associated with FASD and complex trauma. A more robust understanding comparing the neurocognitive profiles of FASD and complex trauma can guide assessment, diagnosis, and interventions to support the long-term management of youth with cognitive impairments. INCLUSION CRITERIA: The review will assess various studies that evaluate the neurocognitive profiles of FASD and complex trauma amongst the pediatric population (aged 0-18). Complex trauma will be defined as multiple interpersonal traumatic events that happen in childhood. The context of this review is pediatric patients diagnosed with FASD or exposed to complex trauma. METHODS: We will search MEDLINE (Ovid), Embase (Ovid), PsycINFO (EBSCO), Scopus and Google Scholar. Additionally, will conduct backwards and forwards citation searching of all included sources. Title and abstract screening and full-text review will be performed by at least two independent reviewers. Data extraction will be performed using a tool developed for this review. The results will be presented in a narrative and tabular format.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.091
metaresearch head score (Gemma)0.088
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.091
Threshold uncertainty score0.480

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0910.088
Meta-epidemiology (narrow)0.0040.005
Meta-epidemiology (broad)0.0140.016
Bibliometrics0.0230.017
Science and technology studies0.0050.004
Scholarly communication0.0090.010
Open science0.0070.008
Research integrity0.0080.005
Insufficient payload (model declined to judge)0.0310.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.135
GPT teacher head0.376
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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