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Record W4412994236 · doi:10.1111/vsu.14321

Outcomes and prognostic variables associated with right divisional hepatic lobectomies in 70 dogs

2025· article· en· W4412994236 on OpenAlexaff
Helen Foster, Brad M. Matz, Janet A. Grimes, Kelley M. Thieman Mankin, Arathi Vinayak, Julius M. Liptak, Daniel S. Linden, Emily J. Kennedy, Kate A. Korchek, Won Suk Kim

Bibliographic record

VenueVeterinary Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicHepatocellular Carcinoma Treatment and Prognosis
Canadian institutionsOttawa Hospital
FundersCollege of Veterinary Medicine, Auburn University
KeywordsMedicinePerioperativeComplicationSurgeryHepatocellular carcinomaLogistic regressionRetrospective cohort studyMedical recordSurvival analysisBlood transfusionInternal medicine

Abstract

fetched live from OpenAlex

OBJECTIVE: To determine the outcome and prognostic variables associated with survival and complications in dogs undergoing right divisional hepatic lobectomies. STUDY DESIGN: Multi-institutional retrospective case series. ANIMALS: A total of 70 client-owned dogs with right divisional hepatic masses. METHODS: Medical records of dogs undergoing right divisional hepatic lobectomies and partial lobectomies from January 1, 2008 to January 1, 2022 were reviewed and key variables were extracted. Univariable logistic regression estimated effects of risk factors. Kaplan-Meier survival curves estimated overall survival times (OST) and median survival times (MST). RESULTS: Intraoperative complications occurred in 38/70 (54.3%) dogs. A total of 15 dogs (21.4%) required blood transfusions. No surgical method was associated with intraoperative (p = .566), immediate postoperative (p = .756), or short-term complications (p = .799). Perioperative mortality risk was 2.9% and 30-day mortality risk was 12.1%. There were differences in survival based on the requirement for advanced hemodynamic support (p = .004). Hepatocellular carcinoma (HCC) was the most common diagnosis at 52.9%. The 1-, 2-, and 3-year survival rates for dogs with HCC were 77%, 55%, and 12%, respectively, with 35.3%, 48.8%, and 65.8% lost to follow-up at 1, 2, and 3 years. CONCLUSION: Right divisional hepatic lobectomies were associated with a high intraoperative complication risk, with 21% of dogs requiring blood transfusions; however, no intraoperative deaths occurred. No surgical method was associated with greater risk of complications. CLINICAL SIGNIFICANCE: Despite high intraoperative complication risks, right divisional lobectomy and partial lobectomy may carry a lower risk of perioperative mortality than previously considered.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.614

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.257
Teacher spread0.201 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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