Update on the Axial Involvement in Psoriatic Arthritis (AXIS) Project
Bibliographic record
Abstract
Psoriatic arthritis (PsA) is an inflammatory disease associated with psoriasis, often affecting both peripheral and axial skeletal structures. Axial symptoms affect a significant portion of individuals with PsA. The Axial Involvement in Psoriatic Arthritis (AXIS) study, a multinational, multicenter cross-sectional study conducted under the umbrella of the Group for Research on Psoriasis and Psoriatic Arthritis (GRAPPA) and Assessment of SpondyloArthritis international Society (ASAS), aimed to establish a unified definition and classification criteria for axial involvement in PsA. The study enrolled 409 patients from 41 centers across 19 countries. Comprehensive clinical and imaging assessments were conducted for each patient including radiographs and magnetic resonance imaging of the sacroiliac joints and spine. Imaging data were reviewed by both local investigators and a central imaging committee. Final judgment on the presence or absence of axial involvement was made by investigators following evaluation of all data by the investigators and the central expert imaging team. Axial involvement was assessed to be present in 112/409 patients (27.4%). Data analysis is ongoing and the full study results are expected shortly. This update was presented at the GRAPPA 2024 annual meeting.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.006 | 0.014 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.004 | 0.003 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.002 | 0.002 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.016 | 0.006 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".