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Record W4413010816 · doi:10.1016/j.intf.2025.100302

Caregiver perspectives on barriers and facilitators to pediatric intestinal failure quality of life

2025· article· en· W4413010816 on OpenAlexaff
Vikram Raghu, Lisa Lakkis, Claire Josey, Flor de Abril Cameron, Daniela Gattini, Beverly Kosmach‐Park, Janel Hanmer

Bibliographic record

VenueIntestinal failure. · 2025
Typearticle
Languageen
FieldMedicine
TopicChildhood Cancer Survivors' Quality of Life
Canadian institutionsSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
FundersNational Center for Advancing Translational SciencesNASPGHAN FoundationNational Institutes of HealthNorth American Society for Pediatric Gastroenterology, Hepatology and Nutrition
KeywordsIntestinal failureQuality of life (healthcare)PsychologyGerontologyMedicineNursingIntensive care medicineParenteral nutrition

Abstract

fetched live from OpenAlex

Background: Caregivers of children with intestinal failure provide unique perspectives on their child's quality of life. This study explores the caregiver perception of barriers and facilitators affecting quality of life in children with intestinal failure and examines how caregiver quality of life may be affected. Material and methods: Semi-structured interviews were conducted with caregivers of children with intestinal failure and transcribed verbatim. An initial codebook was inductively developed by one coder and subsequently reviewed by two additional coders, who applied the codes to all transcripts. Thematic analysis was performed, and a conceptual framework was generated. Results: Interviews were conducted with 10 caregivers (9 biological mothers, 1 biological father). Quality of life domains may be grouped into 3 main categories: mental and psychological well-being, daily routine, and activities. Barriers to quality of life within these categories included differences from peers and siblings, mental health struggles, medical complications, procedures and hospitalizations, traditional school settings, swimming, and travel. Facilitators focused on adapting to these differences through support systems at home and school along with the medical care expertise gained over time. Caregivers faced significant impacts on their own quality of life in the areas of mental health, finances, and social activities. Conclusion: Caregivers offer valuable insight into the barriers and facilitators of their child's QOL within the context of intestinal failure. Multidisciplinary interventions aimed at supporting families as they adapt to their own unique lifestyle may significantly enhance quality of life for both children and caregivers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.010
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0000.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.317
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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