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Record W4413024006 · doi:10.1113/ep092767

Blood flow restriction exercise during microgravity exposure in parabolic flight

2025· article· en· W4413024006 on OpenAlexafffund
Yannick Laflamme, Étienne Chassé, Luke Hughes

Bibliographic record

VenueExperimental Physiology · 2025
Typearticle
Languageen
FieldMedicine
TopicSpaceflight effects on biology
Canadian institutionsCanadian Armed ForcesCanadian Space Agency
FundersCanadian Space Agency
KeywordsBlood flow restrictionMedicineWeightlessnessSquatPhysical medicine and rehabilitationAviation medicineSimulationPhysical therapyResistance trainingComputer sciencePathology

Abstract

fetched live from OpenAlex

Abstract This case report evaluates whether it is possible to perform blood flow restriction (BFR) exercise during exposure to microgravity. The objectives were three‐fold: (1) to determine if a personalised tourniquet system (PTS) hardware technology performs nominally and enables BFR exercise in microgravity; (2) to determine if BFR augments the exercise stimulus in microgravity in a similar manner to its application on Earth; and (3) to evaluate tolerance and acceptability of performing BFR exercise and operating the PTS hardware in microgravity. Two participants performed resistance squat and deadlift exercises on a flywheel device (inertia of 0.01 kg m 2 ) with and without BFR during microgravity in parabolic flight onboard the National Research Council's Falcon 20 aircraft. Heart rate, perceived exertion and discomfort, and the participants’ tolerance and acceptability of performing BFR exercise in microgravity compared to exercise without BFR were measured. Performance of the PTS hardware technology was also evaluated. This case report demonstrates, for the first time, that it is possible to perform BFR exercise in microgravity in a manner that may augment the physiological stress of exercise in an acceptable and tolerable fashion. Importantly, the BFR hardware technology required to perform BFR exercise in an accurate, safe and effective manner performs nominally in microgravity. Future research should aim to conduct investigations during longer exposures to microgravity (i.e. during 3‐ to 6‐month missions on the International Space Station), providing a more comprehensive evaluation of the physiological stimulus provided and the tolerance and acceptability when performing BFR exercise in the space environment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.389
Threshold uncertainty score0.862

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.276
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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