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Record W4413036475 · doi:10.1098/rstb.2024.0091

The evolution of the tree of life

2025· article· en· W4413036475 on OpenAlexafffund
Molly Chen, Artem I. Kholodov, Laura A. Hug

Bibliographic record

VenuePhilosophical Transactions of the Royal Society B Biological Sciences · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsUniversity of Waterloo
FundersCanada Research Chairs
KeywordsTree of life (biology)Tree (set theory)Context (archaeology)Data sciencePhylumSampling (signal processing)TaxonTracingComputer scienceConstruct (python library)EcologyEvolutionary biologyBiologyPhylogeneticsPaleontologyMathematics

Abstract

fetched live from OpenAlex

The tree of life is one of the most important organizing principles in biology. Updates and revisions are historically derived from improved data capture, increasingly refined models of evolution and expanded taxon sampling. Tracing the changes in the tree of life over the molecular era (1990-present) highlights the evolution of biologists' understanding of life on earth and serves as a foil placing the explosion of available data over this timeframe in context. Using current-day information, we explored the taxonomic growth captured in a tree of life through historic tree reconstruction. Data capture is now facilitating improvements in genome quality rather than expanding deep diversity, as the rate of novel phylum discovery is slowing for bacteria and archaea. Using dissimilarity metrics, the proportion of changes that each historic tree encompasses identified a diminishing influence of additional taxa on high-level topological revisions. No trees recapitulated current hypotheses for deep relationships on the tree of life, reflective of disadvantages associated with high taxon sampling and the divide-and-conquer methodologies required to analyse extremely large datasets. This work clarifies the effect of the interaction between data quality, data quantity and taxonomic diversity on our ability to construct a stable tree of life.This article is part of the discussion meeting issue 'Chance and purpose in the evolution of biospheres'.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.028
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.023

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.028
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0020.006
Scholarly communication0.0060.008
Open science0.0010.002
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.251
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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Same venuePhilosophical Transactions of the Royal Society B Biological SciencesSame topicGenomics and Phylogenetic StudiesFrench-language works237,207