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Record W4413055471 · doi:10.2106/jbjs.rvw.25.00086

Predictors of Conversion Total Hip Arthroplasty After Surgically Managed Acetabulum Fractures

2025· review· en· W4413055471 on OpenAlexaff
Geoffrey W Schemitsch, Darius L. Lameire, Graeme Hoit, Manav V. Vyas, Amir Khoshbin, Robert Fowler, Aaron Nauth, Neill K. J. Adhikari

Bibliographic record

VenueJBJS Reviews · 2025
Typereview
Languageen
FieldMedicine
TopicPelvic and Acetabular Injuries
Canadian institutionsHealth Sciences CentreSunnybrook Health Science CentreSt. Michael's HospitalUniversity of Toronto
Fundersnot available
KeywordsMedicineImpactionAcetabulumConfidence intervalSurgeryOdds ratioFemoral headArthroplastyOsteoarthritisInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Operative management of acetabular fractures can be complicated by the development of symptomatic post-traumatic arthritis, which may necessitate conversion total hip arthroplasty (THA). There is increased interest in treatment with THA for acute management, but optimal patient selection depends on identifying those at risk of later symptomatic post-traumatic arthritis requiring conversion THA. METHODS: We systematically reviewed prognostic factors associated with conversion THA in adult patients with operatively managed acetabulum fractures. We searched MEDLINE and EMBASE from inception to September 27, 2024. Screening, data extraction, risk of bias assessment, and evidence grading were completed in duplicate. Data were pooled using a random-effects model to produce summary odds ratios (ORs), hazard ratios (HRs), and mean differences, with 95% confidence intervals (CIs). Risk of bias was assessed using the Quality in Prognosis Studies tool. Certainty of evidence was evaluated using the Grade of Recommendation, Assessment, Development, and Evaluation framework. RESULTS: A total of 3,054 citations were screened, and 38 studies (6,931 fractures) met inclusion criteria. Eight factors were associated with conversion THA in unadjusted analyses: acetabular impaction (OR 2.08, 95% CI 1.60-2.70, moderate certainty), femoral head impaction (OR 2.70, 95% CI 1.80-4.06, moderate certainty), dislocation (OR 2.20, 95% CI 1.51-3.19, moderate certainty), nonanatomic reduction on radiography (OR 2.36, 95% CI 1.58-3.51, moderate certainty), nonanatomic reduction on computed tomography (OR 3.46, 95% CI 1.25-9.57, moderate certainty), associated fracture type (OR 1.76, 95% CI 1.29-2.41, moderate certainty), female sex (OR 1.48, 95% CI 1.15-1.88, moderate certainty), and posterior wall involvement (OR 1.82, 95% CI 1.18-2.80, moderate certainty). In multivariable analyses, age (adjusted OR 1.04, 95% CI 1.02-1.06, high certainty; adjusted HR 1.04, 95% CI 1.03-1.05, high certainty) and femoral head impaction (adjusted HR 3.19, 95% CI 1.16-8.75, moderate certainty) were associated with conversion THA. The weighted proportion of patients requiring THA conversion was 17.6% (95% CI 15.2%-20.4%, low certainty). CONCLUSION: Older age and femoral head impaction were the only factors associated with conversion to THA in univariable and multivariable analyses. LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.067
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.038

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.067
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.004
Bibliometrics0.0050.006
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.321
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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