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Record W4413075855 · doi:10.1016/j.xjtc.2025.06.025

Implementation of Staphylococcus aureus decolonization in cardiac surgery

2025· article· en· W4413075855 on OpenAlexafffund
Dominique de Waard, Ryan Gainer, Claudia Côté, Paul Bonnar, Gregory M. Hirsch

Bibliographic record

VenueJTCVS Techniques · 2025
Typearticle
Languageen
FieldMedicine
TopicSurgical site infection prevention
Canadian institutionsNova Scotia Cancer CentreNova Scotia Health AuthorityIzaak Walton Killam Health CentreNova Scotia Research and Innovation TrustDalhousie University
FundersKillam TrustsDalhousie UniversityDalhousie Medical Research Foundation
KeywordsStaphylococcus aureusDecolonizationMedicineStaphylococcal infectionsMicrobiologyBiologyBacteriaPolitical science

Abstract

fetched live from OpenAlex

Objective: (SA) screening and decolonization is a guideline-recommended treatment for the prevention of surgical site infections in cardiac surgery. This study aimed to formally assess the barriers and facilitators associated with its implementation. Methods: Targeted SA screening and decolonization started at our institution in November 2022. To assess barriers and facilitators to implementation, we conducted focus group interviews informed by the Consolidated Framework for Implementation Research at approximately 6 months after initiation of the intervention. We also regularly collected quantitative data on missed screening and/or decolonization to address gaps in uptake. This was reviewed at 6-month and 1-year time points. Adjustments to implementation were regularly made to address barriers. Results: At 1 year, 563 nonurgent inpatients and 232 outpatients were consulted to cardiac surgery. Ninety-five percent of the inpatients and 91% of the outpatients considered for cardiac surgery were screened appropriately. Of the patients accepted for cardiac surgery, 50% of positive inpatients underwent decolonization in the first 6 months prior to focus groups compared to 67% in the subsequent 6 months. For outpatients, 77% were decolonized in the first 6 months, compared to 79% in the subsequent 6 months. Major barriers to implementation included delays in receiving screening results, difficulty meeting screening and decolonization timelines, and staffing turnover. Conclusions: SA screening and decolonization was successfully implemented as a standard of care at our institution with the aid of an implementation science framework. By engaging care partners and healthcare staff throughout the implementation process and regularly addressing barriers, we developed a sustainable SA screening and decolonization program. Adjustments are ongoing to increase and sustain decolonization uptake.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.382
Threshold uncertainty score0.280

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.349
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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