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Record W4413094307 · doi:10.1002/imhj.70037

Fetal programming of infant temperament: An examination of prenatal maternal stress during the COVID‐19 pandemic

2025· article· en· W4413094307 on OpenAlexafffundabout
Jessica Pearson, Magdalena A. Zdebik, Claire Baudry, Gabrielle Fréchette‐Boilard

Bibliographic record

VenueInfant Mental Health Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicMaternal Mental Health During Pregnancy and Postpartum
Canadian institutionsUniversité du Québec en OutaouaisUniversité du Québec à Trois-RivièresCentre Jeunesse de QuebecInnovation and Economic Development Trois Rivières
FundersSocial Sciences and Humanities Research Council of Canada
KeywordsPandemicTemperamentContext (archaeology)Prenatal stressNegative affectivityPregnancyPsychologyDevelopmental psychologyMedicineCoronavirus disease 2019 (COVID-19)Clinical psychologyPsychiatryGestationPersonalityAnxietyDiseaseSocial psychology

Abstract

fetched live from OpenAlex

Pregnant women were exposed to multiple sources of stress during the COVID-19 pandemic, raising concerns about the potential fetal programming effects of child development. A few studies show that prenatal maternal stress during the pandemic is associated with greater negative affectivity and more extraversion in infants. However, studies investigating this association are very few and need to be replicated. This study aims to prospectively investigate the association between prenatal maternal stress during the COVID-19 pandemic and infant temperament, while assessing the relative contribution of postnatal maternal stress. A total of 269 low-risk, French-speaking women from the province of Quebec, Canada, completed questionnaires during pregnancy to report on their prenatal maternal stress (general and pandemic-related). When their child was 6 months old, the mothers completed a second questionnaire to collect information on postnatal stress and infant temperament. The results show that prenatal maternal stress in the context of the pandemic significantly predicted infants' negative affectivity and orienting/regulation factors, even after controlling for postnatal stress. The results support the fetal programming hypothesis, while highlighting the additional contribution of maternal stress during the child's first months of life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.138
Threshold uncertainty score0.275

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.349
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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Same venueInfant Mental Health JournalSame topicMaternal Mental Health During Pregnancy and PostpartumFrench-language works237,207