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Record W4413100976 · doi:10.1007/s00467-025-06916-w

Contrast-induced acute kidney injury and nephrogenic systemic fibrosis in children

2025· review· en· W4413100976 on OpenAlexaff
Alice Ming-jie Chuah, Jonathan H. Chen, Alison Lap‐tak, Kin Fen Kevin Fung, Eugene Yu-hin Chan

Bibliographic record

VenuePediatric Nephrology · 2025
Typereview
Languageen
FieldMedicine
TopicAcute Kidney Injury Research
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsNephrogenic systemic fibrosisMedicineIodinated contrastAcute kidney injuryRadiologyMagnetic resonance imagingPopulationInternal medicineComputed tomography

Abstract

fetched live from OpenAlex

Intravascular contrast media plays an important role in improving tissue and vascular characterisation in diagnostic imaging and image-guided intervention. Iodinated contrast media are commonly used in imaging modalities which utilise ionising radiation and gadolinium-based contrast agents (GBCA) in magnetic resonance imaging. Intravascular use of iodinated contrast medium is associated with contrast-induced acute kidney injury and GBCA with nephrogenic systemic fibrosis, both of which can lead to potentially significant adverse outcomes in patients with kidney impairment. However, most studies in the literature focus on adults and the evidence in the paediatric population is scarce. In this review, we aim to examine the consensus guidelines and studies in the paediatric population who require intravascular iodinated contrast media and GBCA. At the end, we propose an algorithm to approach the use of intravascular contrast media in children who need to undergo diagnostic imaging or image-guided intervention.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.636
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.001
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.339
Teacher spread0.322 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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