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Record W4413115467 · doi:10.1186/s12903-025-06719-3

Sex and gender differences in periodontal disease: a cross-sectional study in Switzerland

2025· article· en· W4413115467 on OpenAlexaboutno aff
Livia Liechti, Vera Regitz‐Zagrosek, Pimrapat Gebert, Patrick R. Schmidlin, Guglielmo Campus

Bibliographic record

VenueBMC Oral Health · 2025
Typearticle
Languageen
FieldDentistry
TopicOral microbiology and periodontitis research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicinePeriodontitisGingivitisCross-sectional studyPeriodontal diseaseMale genderObservational studyAffect (linguistics)DentistryInternal medicineDemographyPathologyPsychology

Abstract

fetched live from OpenAlex

BACKGROUNDS: The role of sex- and gender-related traits has often been downplayed in clinical studies and periodontal disease is no exception. Sex and gender represent distinct biological and sociocultural factors that may independently influence periodontal disease. These factors can affect the risk and progression of periodontal disease as well as response to treatment. This clinical observational study was designed to evaluate gender distribution and the impact of sex and gender on health of gingival tissue using bleeding on probing and probing depth (Periodontal Screening Index "PSI"). METHODS: Four hundred thirty patients were included in this study. Clinical parameters were retrieved from standard examination and a questionnaire was used to assess gender. Sex was characterized as indicated in the birth certificate, a short version of a Swiss-Canadian gender questionnaire was used for the assessment of gender. In addition, patients were asked about self-attribution of gender and the gender Score (GS) was constructed for each subject. RESULTS: 53.0% (228 patients) were females and 47.0% (202 patients) males. No statistically significant differences were observed regarding sex distribution between the categorization of PSI in two and three groups (p = 0.68 and p = 0.57 respectively). The mean gender score (GS) in the subjects with Gingivitis/Mild Periodontitis was 51.75 ± 41.77 while in the subjects with claimed Periodontitis was 51.74 ± 40.55 (One-way ANOVA F = 0.00 p = 0.98). There was no statistically significant association between GS and periodontitis. CONCLUSIONS: This study is one of the first to examine both sex and gender using a validated score in relation to periodontal disease. The outcomes of the cross-sectional study demonstrate that gender is not an indicator for the presence of periodontal disease in Swiss population, emphasizing the need to consider sex and gender as separate factors in clinical studies. Clinical screening protocols may not need to be adjusted based on gender-related traits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.181
Threshold uncertainty score0.829

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.103
GPT teacher head0.424
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2025
Admission routes1
Has abstractyes

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