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Record W4413115797 · doi:10.1016/j.jhlto.2025.100349

Priorities for lung transplantation research: a James Lind Alliance priority-setting partnership between patients, caregivers, and clinicians in Canada

2025· article· en· W4413115797 on OpenAlexaffabout
K. Halloran, Lea Harper, Nikki J. Marks, Céline Bergeron, Basil Nasir, Dima Kabbani, Laura van den Bosch, A. Hirji, Rhea Varughese, Jason Weatherald

Bibliographic record

VenueJHLT Open · 2025
Typearticle
Languageen
FieldMedicine
TopicTransplantation: Methods and Outcomes
Canadian institutionsVancouver General HospitalUniversity Health NetworkToronto General HospitalCentre Hospitalier de l’Université de MontréalUniversity of CalgaryUniversity of Alberta
Fundersnot available
KeywordsAllianceGeneral partnershipLung transplantationMedicineTransplantationIntensive care medicineGerontologyPolitical scienceSurgery

Abstract

fetched live from OpenAlex

This study employed the James Lind Alliance Priority Setting Partnership methodology to identify and prioritize research priorities in lung transplantation through engagement of pre- and post-lung transplant patients, caregivers, and clinicians in Canada. An initial survey collected 490 questions from 204 respondents, which were collated into 117 summary questions. After removing duplicates and conducting evidence checks, 25 verified uncertainties were discussed at a final workshop, resulting in a consensus-based Top 10 list of research priorities. Key priorities addressed the need to improve immunosuppression regimens, patient education, lung allograft dysfunction, and donor lung availability. This first-of-its-kind initiative in lung transplantation created a stakeholder-driven research agenda that better aligns future research with patient needs. The findings establish a foundation for more patient-centered lung transplantation research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.196
metaresearch head score (Gemma)0.146
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.817
Threshold uncertainty score0.992

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1960.146
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0060.007
Science and technology studies0.0390.008
Scholarly communication0.0190.007
Open science0.0040.027
Research integrity0.0030.006
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.111
GPT teacher head0.451
Teacher spread0.340 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designQualitative
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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