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Record W4413133260 · doi:10.5539/ijc.v17n2p77

Labile Iron Controllng Therapy To Prevent Cancers and Alzheimer’s Disease

2025· article· en· W4413133260 on OpenAlexvenueno aff
Yuzo Nishida

Bibliographic record

VenueInternational Journal of Chemistry · 2025
Typearticle
Languageen
FieldEngineering
TopicGraphene and Nanomaterials Applications
Canadian institutionsnot available
Fundersnot available
KeywordsChemistryChelationDiseaseZincTransferrinBiochemistryCombinatorial chemistryBiophysicsCancer researchOrganic chemistryInternal medicine

Abstract

fetched live from OpenAlex

It has been pointed out that so-called plasma labile iron (or NTBI = non-transferrin-bound iron) is the essential cause of many cancers and Alzheimer’s disease, but its actual properties have not been clarified. Nishida have concluded that the structure of highly toxic plasma labile iron is an oxo-bridged diiron species through the experimental results using many artificial iron chelating agents. Based on this result, he synthesized non-toxic chelating agents (SP9 and SP10) that prevent the formation of the oxo-bridged di-iron species, and found that these chelates effectively suppress the proliferation of various types of cancers, proving the correctness of his conclusion. He also obtained many related results which support that SP9 and SP10 can be applied to prevent Alzheimer’s disease. Furthermore, Nishida have demonstrated that some zinc ions can remove these dangerous oxo-bridged diiron species through the formation of iron deposition. Nishida have shown that his universal healthcare, so-called “Labile Iron Controllng Therapy” (LICT), which prevents cancers and Alzheimer’s disease through suppressing the formation of dangerous oxo-bridged di-iron species in the human body, can be achieved through daily diet that contain suitable zinc ions and natural lignin derivatives.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.253
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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