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Record W4413182575 · doi:10.1101/2025.08.08.25333289

WHO Infection Prevention and Control Health Facility Rapid Assessment Tool for Ebola and Marburg Diseases: a validation mixed-method study

2025· preprint· en· W4413182575 on OpenAlexaff
Patrick Mirindi, Maria Clara Padoveze, Stacey Mearns, Victoria Willet, Rony Bahatungire, Elizabeth Katwesigye, Michael Mutegeki, Geofrey M. Bukombi, Alex Wasomoka, Patrick Kafeero, Emmanuel Damba, Brian Kasuzi Omongole, Marvin Malikisi, Judith Nanyondo, Rebecca Suubi, Latifatu Mohammed, Diana Atwine, Doreen Nabawanuka, Dorothy Kabasinguzi Byaruhanga, Anita Enane, Deborah Barasa, Tendai Makamure, B Ndoye, Jane Ruth Aceng-Ocero, Landry Cihambanya, Charles Olaro, April Baller

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMarburg virusVirologyMedicineEbola virusOutbreak

Abstract

fetched live from OpenAlex

Abstract Introduction/Objectives: The global population continually faces pathogenic threats from multiple outbreaks annually. These outbreaks may challenge healthcare facilities’ (HF) capacity to provide care while maintaining patients’ and health workers’ safety. Effective infection prevention and control measures are the cornerstone to mitigating and controlling public health events. This study validates the World Health Organization (WHO) IPC health facility rapid assessment tool (RAT) designed for evaluating health facility IPC preparedness and response during Orthoebolavirus disease (EBOD) or Orthomarburgvirus disease (MARD) outbreaks. Methods: This operational research study used a mixed method, combining a prospective evaluation of inter-rater reliability assessment of HF and FGD of assessors. Three assessors applied RAT independently in 51 health facilities in Uganda during the 2022 Sudan virus outbreak. Results: The tool proved feasible to administer, with a median completion time of 62 minutes per facility. The IPC RAT exhibited good internal consistency and inter-rater reliability, with an average Fleiss’ Kappa of 0.4 across the 15 components, suggesting a moderate-to-high consistency among assessors. Recommendations for improving the tool included revising some items for clarity and relevance, adding items to cover additional IPC aspects, developing a user guide and training materials, enhancing the scoring system, data visualization, and analysis dashboard. Conclusion: The IPC EBOD-RAT is a reliable tool for rapidly assessing IPC in HF, during EBOD/MARD outbreaks. This study highlights the need to further refine the tool in various settings and contexts, and to develop user guidance and training materials.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.106
metaresearch head score (Gemma)0.103
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.106
Threshold uncertainty score0.563

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1060.103
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.004
Bibliometrics0.0020.001
Science and technology studies0.0020.001
Scholarly communication0.0020.002
Open science0.0020.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.428
Teacher spread0.395 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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