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Record W4413189510 · doi:10.3390/jcm14165713

Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) for Gynecological Procedures in Obese Patients: A Systematic Review

2025· review· en· W4413189510 on OpenAlexaboutno aff
Aristotelis-Marios Koulakmanidis, Christos Vrysis, D. Zacharakis, Evangelia Kontogeorgi, Ioakeim Sapantzoglou, Charalampos Voros, Athanasios Gkirgkinoudis, Christos Damaskos, Nikolaos Garmpis, Gerasimos Tsourouflis, Stylianos Kykalos, Themos Grigoriadis, Stavros Athanasiou, Dimitrios Dimitroulis

Bibliographic record

VenueJournal of Clinical Medicine · 2025
Typereview
Languageen
FieldMedicine
TopicMinimally Invasive Surgical Techniques
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineNatural orifice transluminal endoscopic surgeryPerioperativeLaparoscopyLaparotomySurgeryCochrane LibraryVaginaPessaryGeneral surgeryRandomized controlled trial

Abstract

fetched live from OpenAlex

Aim: This study was conducted to determine the feasibility, safety, and clinical outcomes of the vaginal natural-orifice transluminal endoscopic surgery (vNOTES) approach in gynecology for obese patients. Methods: PubMed, Cochrane Library, and Google Scholar were searched, from inception to April 2025. A systematic review was performed following the PRISMA guidelines. Studies assessing the use of vNOTES for gynecological procedures in obese women were included. The quality of included articles was evaluated according to the Newcastle–Ottawa Scale. Results: The search yielded three retrospective cohort studies, one cross-sectional, and ten case series. The patients in the vNOTES group (n = 99) had statistically significant shorter operative times, reduced hospitalization, lower postoperative pain scores, fewer perioperative complications, and improved quality of life when compared to the laparoscopy group (n = 84). A study compared obese women to non-obese women undergoing vNOTES and found that operative times were longer in the obese group. Conversion to laparoscopy or laparotomy occurred in fewer than 5% of cases, and intraoperative and postoperative complication rates were low across all studies. Conclusions: vNOTES appears to be safe and potentially superior to other minimally invasive techniques. The small sample size of the case series and the lack of a sufficient number of comparative studies limit the strength of the conclusions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.239
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Meta-epidemiology (broad), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.227
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0120.239
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0200.004
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.126
GPT teacher head0.491
Teacher spread0.365 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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