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Record W4413235523 · doi:10.1016/j.prdoa.2025.100387

Validation of the English version of the Parkinson Anxiety Scale in two Canadian Parkinson’s disease samples

2025· article· en· W4413235523 on OpenAlexafffundabout
Joyce S. T. Lam, Kira Tosefsky, Xuyan Tang, Dylan Meng, Petra Uzelman, Fabricio Pio, Nicholas J. Ainsworth, Fidel Vila‐Rodriguez, Andrew Howard, Silke Appel‐Cresswell

Bibliographic record

VenueClinical Parkinsonism & Related Disorders · 2025
Typearticle
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsUniversity of British Columbia
FundersUniversity of British ColumbiaWeston Family FoundationInstitute of Mental Health, University of British ColumbiaParkinson's Foundation
KeywordsParkinson's diseasePsychologyAnxietyScale (ratio)Clinical psychologyDiseasePsychiatryMedicineCartographyGeographyPathology

Abstract

fetched live from OpenAlex

Introduction: The 12-item Parkinson Anxiety Scale (PAS) assesses the severity of anxiety symptoms in people with Parkinson's disease (PwP). However, psychometric evidence supporting the English self-rated PAS remains largely limited to validation studies by the developers. This study aimed to reinforce validation of this scale through a comprehensive psychometric evaluation in PwP in Canada. Methods: Data were drawn from two Canadian samples of 130 and 53 PwP, respectively, at a tertiary center. Acceptability, reliability, validity, and factor structure were assessed. The Mini International Neuropsychiatric Interview was administered to confirm anxiety diagnoses. Optimal cut-off scores suggesting the presence of an anxiety disorder were determined using receiver operating characteristic (ROC) curve analysis. Results: The PAS and its three subscales demonstrated good acceptability and internal consistency reliability (Cronbach's α > 0.70). Good convergent validity with the State-Trait Anxiety Inventory and divergent validity with scales assessing other non-motor symptoms were obtained. Confirmatory factor analysis supported the three-factor structure (comparative fit index = 0.987; Tucker-Lewis index = 0.983; root mean square error of approximation = 0.083; standardized root mean square residual = 0.087). Optimal cut-off scores were 12.5 for the total PAS (area under the ROC curve = 0.81, sensitivity = 0.89, specificity = 0.58), 8.5 for the persistent anxiety subscale, and 2.5 for the episodic anxiety and avoidance behavior subscales. Approximately 22 % of participants in the larger sample had a diagnosed anxiety disorder. Conclusion: The English self-rated PAS is a valid and reliable instrument for screening and assessing severity and dimensions of anxiety in PwP.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.258
Threshold uncertainty score0.996

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.295
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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