Characteristics of Myopic Traction Maculopathy in the Aier-SERI High Myopia Adult Cohort Study
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Bibliographic record
Abstract
Purpose: To describe the prevalence, clinical characteristics, associations, and visual outcomes of myopic traction maculopathy (MTM), which was defined by the presence of retinoschisis (RS), macular holes (MHs), or foveal retinal detachment (RD), in an adult high myope cohort in Changsha, China.Design: A cross-sectional study.Participants: Chinese adults with high myopia (defined as spherical equivalent [SE] less than or equal to -5 diopters [D]) in the Aier-Singapore Eye Research Institute High Myopia Adult Cohort Study, which is a prospective population-based study.Methods: Swept-source OCT was performed to detect RS, MH, and foveal RD.Multivariable generalized estimating equation analyses were performed to assess associations of MTM and the impact of MTM on best-corrected visual acuity (BCVA).Main Outcome Measures: Prevalence, clinical characteristics, associations, and visual outcomes of MTM.Results: Of 437 participants (839 eyes), MTM was observed in 20 participants with a prevalence of 4.6% (by participants) or in 24 eyes (with a prevalence of 2.9%; by eyes).Overall, the whole cohort (64.7% female) had a mean age of 42.9 ± 7.2 years, an SE of -9.5 ± 4.4 D, and an axial length (AL) of 27.3 ± 1.9 mm.Retinoschisis was the most common lesion (91.7%; 22/24 eyes with MTM).In the multivariable analysis, the prevalence of MTM was associated with a more myopic SE (odds ratio [OR]: 1.09; 95% confidence interval [CI]: 1.01-1.18;P = 0.03), longer AL (OR: 1.30; 95% CI: 1.03-1.65;P = 0.03), myopic macular degeneration (MMD) (OR: 12.77; 95% CI: 3.18-51.24;P < 0.001), and older age (OR: 1.06; 95% CI: 1.01-1.11;P = 0.01).In the multivariable analysis, the prevalence of MTM was also associated with poorer BCVA (beta coefficient: -0.07; 95% CI: -0.13 to -0.01; P < 0.01).Conclusions: The prevalence of MTM was 4.6% in an adult high myope cohort.Associations with MTM include more myopic SE, longer AL, MMD, and older age.Myopic traction maculopathy is associated with poorer vision.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it