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Record W4413292006 · doi:10.1016/j.rehab.2025.102006

Cardiorespiratory exercise during rehabilitation is associated with improved functional recovery early post-stroke: A cohort study

2025· article· en· W4413292006 on OpenAlexafffund
Sarah Thompson, Augustine Joshua Devasahayam, Cynthia J. Danells, David Jagroop, Elizabeth L. Inness, Avril Mansfield

Bibliographic record

VenueAnnals of Physical and Rehabilitation Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsUniversity Health NetworkOntario Brain InstituteSunnybrook Health Science CentreToronto Rehabilitation Institute
FundersCanadian Institutes of Health ResearchBranch Out Neurological Foundation
KeywordsCardiorespiratory fitnessRehabilitationPhysical medicine and rehabilitationStroke (engine)MedicinePhysical therapyCohortCohort studyInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Cardiorespiratory exercise (CRE) early post-stroke can improve cardiorespiratory fitness, facilitate participation in rehabilitation, and promote neuroplasticity. OBJECTIVES: This study aimed to determine if CRE during routine inpatient stroke rehabilitation is associated with improved recovery of motor and cognitive function, functional ambulation, and motor impairment. METHODS: People (n = 503) admitted to 2 rehabilitation hospitals over 14 months were included in this cohort study. Participants were classified into 3 groups: "Prescribed," where participants completed CRE that was included in their treatment plan; "Incidental," where they completed CRE that was not included in their treatment plan; and "None," where they did not complete any CRE. Analysis of covariance compared Functional Independence Measure (FIM), Functional Ambulation Category (FAC), and Chedoke-McMaster Stroke Assessment (CMSA) scores between groups at discharge, controlling for age, length of stay, comorbidities and scores at baseline. Multiple linear regression determined the relationship between time spent doing CRE during rehabilitation and admission to discharge change in FIM, FAC and CMSA scores, controlling for age, length of stay, comorbidities, and site. RESULTS: The Prescribed group had higher FIM total and motor sub-scores at discharge than the None (Site A; P < 0.001) or the Incidental group (Site B; P < 0.03). There were significant positive correlations between time spent doing CRE during rehabilitation and change in all outcomes (r > 0.15), except CMSA hand scores. CONCLUSIONS: Findings support that CRE during routine inpatient rehabilitation early post-stroke is associated with improved functional independence, ambulation and motor recovery. However, given that the observational design limits causal inferences, controlled studies are needed to confirm the benefits of CRE early post-stroke.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.013
Threshold uncertainty score0.026

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.281
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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