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Record W4413298377 · doi:10.1016/j.ajo.2025.08.031

Controversies, Consensuses, and Guidelines on Preventing, Diagnosing and Managing Acute-onset Bacterial Endophthalmitis after Cataract Surgery by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII)

2025· article· en· W4413298377 on OpenAlexaff
Aafreen Bari, Srinivas K. Rao, Rupesh Agrawal, Penny Allen, John Buchán, Andrew Chang, David F. Chang, Soon‐Phaik Chee, Weirong Chen, Kuan‐Jen Chen, Vanissa W. S. Chow, Taraprasad Das, Vivek Pravin Dave, Harry W. Flynn, Tina Felfeli, Adrian T. Fung, Andrzej Grzybowski, Mary Ho, Wai‐Ching Lam, Liying Low, Mats Lundström, William F. Mieler, Nishant Radke, Paisan Ruamviboonsuk, Landon J. Rohowetz, Savitri Sharma, Tarun Sharma, Takashi Suzuki, Chi Wai Tsang, Ke Yao, Alvin L. Young, Mingzhi Zhang, Ke Zheng, Dennis S.C. Lam

Bibliographic record

VenueAmerican Journal of Ophthalmology · 2025
Typearticle
Languageen
FieldMedicine
TopicOcular Infections and Treatments
Canadian institutionsUniversity of British ColumbiaToronto Rehabilitation InstituteUniversity of Toronto
FundersAlconChinese University of Hong KongCooperVision
KeywordsAsia pacificEndophthalmitisOphthalmologyMedicineOptometryCataract surgeryHistoryEthnology

Abstract

fetched live from OpenAlex

BACKGROUND: Postcataract surgery endophthalmitis is a serious but largely preventable clinical entity. The implementation of uniform preoperative, intraoperative, and postoperative protocols is essential to reduce its incidence. METHODS: In light of emerging evidence and considerable variability in clinical practices, a panel of international experts from the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII) convened to develop evidence-based guidelines addressing all phases of cataract surgery. This consensus manuscript is the product of a systematic review of the current literature, informed by the collective experience and expertise of the panel members. The panel engaged in structured discussions, critical evaluation of clinical data, and formal voting to establish agreement across three key domains: (1) preoperative and intraoperative prophylactic strategies, (2) diagnostic approaches for early postoperative acute bacterial endophthalmitis, and (3) standardized management protocols. Voting on each proposed statement was conducted using a 5-point Likert scale (strongly agree, agree, neutral, disagree, strongly disagree). Consensus was defined as ≥75% of experts voting either "strongly agree" or "agree." RESULTS: A total of 45 consensus statements were evaluated, of which 21 (46.6%) achieved the predefined level of consensus. CONCLUSIONS: This document aims to establish standardized guidelines to improve cataract surgery outcomes by minimizing the risk of postoperative endophthalmitis. For areas where consensus was not achieved, the panel recommends further investigation and continued research to guide future updates to clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.049
metaresearch head score (Gemma)0.144
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.049
Threshold uncertainty score0.260

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0490.144
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0050.004
Science and technology studies0.0040.006
Scholarly communication0.0080.007
Open science0.0060.005
Research integrity0.0100.019
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.311
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractno

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