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Record W4413309533 · doi:10.7759/cureus.90221

Clinical Impact of Neuropostural and Neuromuscular Optimization Protocols With Radio Electric Asymmetric Conveyer (REAC) Technology in Older Adults With Femoral Fractures: An Observational Study

2025· article· en· W4413309533 on OpenAlexaff
Bruna Lombardi, Margherita Imbrenda, Valtere Giovannini, Vania Fontani, Salvatore Rinaldi

Bibliographic record

VenueCureus · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlanarian Biology and Electrostimulation
Canadian institutionsHealth Care Foundation
Fundersnot available
KeywordsMedicineRehabilitationObservational studyVisual analogue scalePhysical medicine and rehabilitationAdverse effectPhysical therapyNeuromodulationInternal medicine

Abstract

fetched live from OpenAlex

Background: Femoral fractures in the elderly often result in long-lasting disability. Standard rehabilitation may fail to address neurofunctional alterations such as functional dysmetria (FD), which limit optimal motor recovery. This study evaluates the clinical utility of Radio Electric Asymmetric Conveyer (REAC) neuromodulation protocols, Neuro Postural Optimization (NPO) and Neuro Muscular Optimization (NMO), as adjuncts to standard rehabilitation in elderly patients post femoral fracture surgery. Methods: This observational study was conducted at Casa di Cura Villa Fiorita (59100, Prato, Italy), within a clinical-scientific collaboration program with the Rinaldi Fontani Institute. Fourteen elderly patients (mean age 81.7 years) received one NPO session, followed by 10 NMO sessions in conjunction with standard physiotherapy. A matched historical control group (n = 14) received only conventional therapy. Assessed parameters included the Barthel Index (BI), Visual Analogue Scale (VAS) for pain, FD presence, and hospital length of stay. Statistical analysis used paired/unpaired t-tests (p < 0.05). Results: FD was completely resolved in all REAC-treated patients following the single NPO session. This neurobiological modulation likely restores subcortical and cerebellar network homeostasis, enabling symmetrical motor output. The NMO protocol supported neuromotor pattern optimization throughout recovery. Compared to controls, the REAC group achieved significantly greater improvements in BI (+47.1 vs. +38.1 points, p = 0.006), pain reduction (-5.2 vs. -3.6, p < 0.001), and shorter hospital stay (-2.2 days, p = 0.027). No adverse effects were reported. Conclusions: The integration of REAC NPO and NMO protocols into conventional rehabilitation enhanced motor symmetry, pain control, and recovery speed. These findings justify further randomized trials and suggest REAC neuromodulation as a valuable, non-invasive, and scalable strategy in orthopedic rehabilitation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.474

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.361
Teacher spread0.338 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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