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Record W4413341150 · doi:10.3171/case25274

Prenatal diagnosis and conservative management of a congenital cavernous sinus infantile hemangioma: illustrative case

2025· article· en· W4413341150 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Neurosurgery Case Lessons · 2025
Typearticle
Languageen
FieldMedicine
TopicVascular Malformations Diagnosis and Treatment
Canadian institutionsCentre Hospitalier Universitaire Sainte-JustineUniversité de MontréalUniversité de SherbrookeUniversité Laval
Fundersnot available
KeywordsMedicineHemangiomaConservative managementPrenatal diagnosisSurgeryPregnancyFetus

Abstract

fetched live from OpenAlex

BACKGROUND: Infantile hemangiomas (IHs) are the most common benign vascular tumors of infancy, although intracranial IHs remain exceedingly rare. Diagnosis is typically postnatal, with some cases requiring medical or surgical intervention. Here, the authors report the first case of a congenital cavernous sinus IH diagnosed via prenatal imaging and managed conservatively with successful spontaneous regression. OBSERVATIONS: A 28-year-old female underwent routine fetal ultrasound at 32 weeks' gestation, revealing a 1.8-cm perithalamic lesion. Fetal MRI at 33 weeks confirmed an extra-axial mass in the right middle fossa with a dural attachment. Postnatal MRI on day 1 of life demonstrated imaging features consistent with an IH. Given the neonate's asymptomatic status, conservative management was pursued. Serial MRI at 10 weeks and 6 months showed progressive lesion regression, with near-complete resolution. The infant remained asymptomatic with normal neurodevelopmental progress. LESSONS: This case highlights the potential for spontaneous regression of congenital intracranial IHs diagnosed prenatally. Despite the risk of bleeding, conservative management with close clinical and radiological follow-up may be a viable option in select asymptomatic cases, particularly in the neonatal period when surgical risks are significant. https://thejns.org/doi/10.3171/CASE25274.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.071
Threshold uncertainty score0.591

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.303
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it