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Record W4413362641 · doi:10.3389/fninf.2025.1609077

Large language models can extract metadata for annotation of human neuroimaging publications

2025· article· en· W4413362641 on OpenAlexaff
Matthew D. Turner, Abhishek Appaji, Nibras Ar Rakib, Pedram Golnari, Arcot Rajasekar, Anitha Rathnam K. V, Satya S. Sahoo, Yue Wang, Lei Wang, Jessica A. Turner

Bibliographic record

VenueFrontiers in Neuroinformatics · 2025
Typearticle
Languageen
FieldComputer Science
TopicTopic Modeling
Canadian institutionsUniversity of Toronto
FundersNational Institute on Drug Abuse
KeywordsAnnotationMetadataComputer scienceInformation retrievalUSableNatural language processingNeuroimagingArtificial intelligenceData scienceWorld Wide WebPsychology

Abstract

fetched live from OpenAlex

We show that recent (mid-to-late 2024) commercial large language models (LLMs) are capable of good quality metadata extraction and annotation with very little work on the part of investigators for several exemplar real-world annotation tasks in the neuroimaging literature. We investigated the GPT-4o LLM from OpenAI which performed comparably with several groups of specially trained and supervised human annotators. The LLM achieves similar performance to humans, between 0.91 and 0.97 on zero-shot prompts without feedback to the LLM. Reviewing the disagreements between LLM and gold standard human annotations we note that actual LLM errors are comparable to human errors in most cases, and in many cases these disagreements are not errors. Based on the specific types of annotations we tested, with exceptionally reviewed gold-standard correct values, the LLM performance is usable for metadata annotation at scale. We encourage other research groups to develop and make available more specialized "micro-benchmarks," like the ones we provide here, for testing both LLMs, and more complex agent systems annotation performance in real-world metadata annotation tasks.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.095
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.982
Threshold uncertainty score0.097

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0180.095
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0080.005
Science and technology studies0.0010.001
Scholarly communication0.0050.008
Open science0.0020.005
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0070.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.291
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSimulation or modeling
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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