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Record W4413442130 · doi:10.1111/trf.18386

<i>Babesia</i> nucleic acid prevalence among blood donors in southern Québec

2025· article· en· W4413442130 on OpenAlexaffabout
Christian Renaud, Milena Fedorova, Nathalie Simard, Jean‐François Côté, Jeffrey M. Linnen, Geneviève Baron, François Milord, Karine Thivierge, Alejandra Irace‐Cima, Jamel A. Groves, Rebecca L. Townsend, Paula Saá, Laura Tonnetti, Susan L. Stramer, Marc Germain, Antoine Lewin

Bibliographic record

VenueTransfusion · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicVector-borne infectious diseases
Canadian institutionsMcGill UniversityUniversité de MontréalSanté MontérégieSte. Anne's HospitalCentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-MontréalUniversité de SherbrookeInstitut National de Santé Publique du QuébecHéma-Québec
Fundersnot available
KeywordsNucleic acidBabesiaVirologyMedicineBiologyGenetics

Abstract

fetched live from OpenAlex

BACKGROUND: Tick-borne diseases are on the rise in Canada, and southern Québec is considered one of the highest-risk regions for Babesia emergence. Babesia is easily transmissible through blood transfusion and was the most common transfusion-transmitted infection in the United States before the implementation of nucleic acid testing (NAT) in 2020. Babesia NAT is not yet implemented in Canada, and prevalence studies are necessary for risk assessment. Therefore, Héma-Québec performed a new prevalence study in the summer of 2024. STUDY DESIGN AND METHODS: Whole blood and platelet donors were sampled between June 1, 2024, and October 31, 2024, in four high-risk administrative regions in southern Québec (i.e., Estrie, Montérégie, Montréal, and Mauricie-Centre-du-Québec). The samples were tested at the American Red Cross with a qualitative Babesia NAT, i.e., the Procleix Babesia assay. RESULTS: A total of 28,800 donations were collected and tested from four high-risk administrative regions of the province of Quebec. All donations tested negative for Babesia NAT. DISCUSSION: While public health data indicate that Babesia microti is emerging in southern Québec, to date, the risk of acquiring babesiosis through transfusion of blood products remains low. Partnership with public health authorities and clinicians remains essential to keep abreast of the emergence of such cases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.107

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.206
Teacher spread0.201 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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