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Record W4413448384 · doi:10.1007/s11547-025-02028-5

Application of artificial intelligence in the diagnosis of scaphoid fractures: impact of automated detection of scaphoid fractures in a real-life study

2025· article· en· W4413448384 on OpenAlexaff
A. Ferrer, Chandra Bortolotto, Luisa Carone, Emma Maria Preda, Cristina Fichera, Alice Lionetti, Giulia Gambini, Federico Alberto Grassi, Lorenzo Preda

Bibliographic record

VenueLa radiologia medica · 2025
Typearticle
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsUniversity Hospital Foundation
FundersUniversità degli Studi di Pavia
KeywordsScaphoid fractureMedicineScaphoid boneArtificial intelligenceOrthodonticsWristComputer scienceSurgery

Abstract

fetched live from OpenAlex

PURPOSE: We evaluated the diagnostic performance of two AI software programs (BoneView and RBfracture) in assisting non-specialist radiologists (NSRs) in detecting scaphoid fractures using conventional wrist radiographs (X-rays). METHODS: We retrospectively analyzed 724 radiographs from 264 patients with wrist trauma. Patients were classified into two groups: Group 1 included cases with a definitive diagnosis by a specialist radiologist (SR) based on X-rays (either scaphoid fracture or not), while Group 2 comprised indeterminate cases for the SRs requiring a CT scan for a final diagnosis. Indeterminate cases were defined as negative or doubtful X-rays in patients with persistent clinical symptoms. The X-rays were evaluated by AI and two NSRs, independently and in combination. We compared their diagnostic performances using sensitivity, specificity, area under the curve (AUC), and Cohen's kappa for diagnostic agreement. RESULTS: Group 1 included 174 patients, with 80 cases (45.97%) of scaphoid fractures. Group 2 had 90 patients, of which 44 with uncertain diagnoses and 46 negative cases with persistent symptoms. Scaphoid fractures were identified in 51 patients (56.67%) in Group 2 after further CT imaging. In Group 1, AI performed similarly to NSRs (AUC: BoneView 0.83, RBfracture 0.84, NSR1 0.88, NSR2 0.90), without significant contribution of AI to the performance of NSRs. In Group 2, performances were lower (AUC: BoneView 0.62, RBfracture 0.65, NSR1 0.46, NSR2 0.63), but AI assistance significantly improved NSR performance (NSR2 + BoneView AUC = 0.75, p = 0.003; NSR2 + RBfracture AUC = 0.72, p = 0.030). Diagnostic agreement between NSR1 with AI support and SR was moderate (kappa = 0.576), and substantial for NSR2 (kappa = 0.712). CONCLUSIONS: AI tools may effectively assist NSRs, especially in complex scaphoid fracture cases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.175
Threshold uncertainty score0.991

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.450
Teacher spread0.396 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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