Individual variability in the nuclei of the human superior olivary complex
Why this work is in the frame
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Bibliographic record
Abstract
The superior olivary complex (SOC) receives auditory information from the cochlear nuclei. In nonhuman mammals, the SOC contains three nuclei: the lateral and medial superior olives (LSO, MSO) and the medial nucleus of the trapezoid body (MNTB). There are also periolivary neurons that are assigned to different nuclei in different mammals. The configuration of the SOC in the human differs from that in other species. The LSO is less well-defined; some authors do, and others do not, find an MNTB, and different authors recognize different periolivary nuclei. We have studied the organization of the human SOC using Nissl and immunostained sections of 12 brains from the Witelson Normal Brain Collection. We found an MSO in all cases although it varied in rostro-caudal extent. We did not consistently see a grouping of neurons consistent with an LSO in Nissl sections. Calbindin (CB) is expressed in neurons of the MNTB in several species. We found CB-immunoreactive (ir) cells in all human cases, some in the expected location of the MNTB, however these CB-ir neurons varied in number and location among cases. The variability in SOC configuration suggests there may also be individual variability in sound localization, a major function mediated by the SOC.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it