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Record W4413491735 · doi:10.1038/s41598-025-16442-2

Caste- and environment-associated differential expression of olfactory receptors in pest ants

2025· article· en· W4413491735 on OpenAlexaff
Kayli R. Sieber, Maya Saar, Nicholas Newell, Katrina Fernandez, Flávia P. Franco, Fernando Sujimoto, Charlotte B. Francoeur, Cameron R. Currie, José Maurício S. Bento, Hua Yan

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldNeuroscience
TopicNeurobiology and Insect Physiology Research
Canadian institutionsMcMaster University
FundersNational Institute on Deafness and Other Communication DisordersNational Institutes of Health
KeywordsBiologyForagingTranscriptomeOlfactionPEST analysisIntegrated pest managementOlfactory systemEcologyEvolutionary biologyNeuroscienceGeneGene expressionGeneticsBotany

Abstract

fetched live from OpenAlex

As human society continues to grow and evolve, so does the need for effective pest management strategies. Olfactory-mediated control methods, such as attractant and repellent compounds, are a proposed strategy for mitigating the damaging effects of some insect pests, most notably ants, that rely on olfaction for communication. To develop such compounds, it is first important to comprehensively understand the target species' olfactory transcriptome in order to guide future targeted functional characterization of relevant olfactory proteins. Here, we perform bulk RNA-seq analysis of antennae from three notable pest ant species, Camponotus floridanus, Atta sexdens, and Atta cephalotes. Specifically, we highlight the expression profiles of olfactory receptor genes, as they may serve as potential targets of future industry research and application. We find that the ant antennal transcriptome differs between each species' castes, potentially reflecting varying behaviors and tasks, and also appears to be influenced by the surrounding environment. Our findings suggest a general up-regulation of olfactory receptor genes amongst foraging castes, also demonstrating that, when comparing foraging ants from differing environments, olfactory-related genes exhibit considerable patterns of differential expression. These findings suggest variable olfactory sensitivity depending on the aforementioned factors, warranting further investigation into whether differing caste and environmental conditions may negatively influence the effectiveness of broad-range olfactory-mediated pest management strategies. Development of pest management tools that target specific groups of insects by environment or caste may lead to more effective control.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.272
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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