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Record W4413510013 · doi:10.1097/bsd.0000000000001919

Subsidence Following Anterior-Only Anterior Cervical Corpectomy Fusion For Cervical Spondylotic Myelopathy

2025· article· en· W4413510013 on OpenAlexaff
Rakesh Kumar, Aiyush Bansal, Annie Z. Luo, Kenneth Nwosu, Anirudh K. Gowd, Murad Alostaz, Jean‐Christophe Leveque, Venu M. Nemani, Philip K. Louie

Bibliographic record

VenueClinical Spine Surgery A Spine Publication · 2025
Typearticle
Languageen
FieldMedicine
TopicCervical and Thoracic Myelopathy
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsCorpectomyMedicineSurgeryMeta-analysisIncidence (geometry)Anterior cervical discectomy and fusionInternal medicineCervical spine

Abstract

fetched live from OpenAlex

STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To examine the occurrence and potential contributing factors of interbody subsidence following anterior-only ACCF performed for CSM. SUMMARY OF BACKGROUND DATA: Surgical interventions for cervical spondylotic myelopathy (CSM) frequently involve anterior approaches, such as anterior cervical discectomy/fusion (ACDF) or anterior cervical corpectomy/fusion (ACCF). Although graft subsidence is a well-established and described complication in ACDF procedures, much less has been published regarding factors related to subsidence in patients undergoing anterior-only ACCF for CSM. METHODS: A systematic literature search was conducted using PubMed, Embase, and COCHRANE. The study's inclusion criteria encompassed anterior-only anterior cervical corpectomy and fusion (ACCF), surgery for the primary diagnosis of cervical spondylotic myelopathy (CSM). Qualitative analysis was performed for complications and revision rates. The data were subjected to meta-analysis to evaluate subsidence incidence rates, and meta-regression analysis was used to assess variations between different graft types. RESULTS: Two hundred forty-five abstracts were evaluated and 34 papers met the inclusion criteria. Two thousand five patients were evaluated over a mean of 31 months (range: 6-56 mo). Pooled subsidence rates expressed as incidence per person-years based on graft type were as follows: 2% (carbon fiber), 27% (fibular strut allograft), 2% (nHAPA composite strut), 5% (PEEK), 10% (static titanium), and 2% (expandable titanium cages). The combined subsidence rate for all grafts was 7%. Notably, the expandable titanium cohort demonstrated a lower subsidence rate (2%) compared with the overall pooled cohort (7%), while other graft types showed no significant difference. CONCLUSION: Subsidence occurred in ∼7% of patients undergoing anterior-only ACCF procedures for CSM. Notably, the use of expandable metal cages resulted in a lower rate of subsidence compared with the broader cohort. This finding suggests that these implant options may be preferable to reduce the risk of subsidence when corpectomy is necessary without posterior fixation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.600
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.367
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

Explore more

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