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Record W4413611875 · doi:10.1002/acr.25635

Identifying High‐Impact Solutions to Address Racial and Ethnic Health Disparities in Lupus: A Consensus‐Based Approach

2025· article· en· W4413611875 on OpenAlexafffund
Joy Buie, Michael Fisher, Kristen Backor, Hannah Tyldsley, Ashira Blazer, Candace H. Feldman, Andrea Knight, S. Sam Lim, B. Frank Polk, Ed Yelin, Edith M. Williams, Karen H. Costenbader

Bibliographic record

VenueArthritis Care & Research · 2025
Typearticle
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
FundersEMD SeronoMallinckrodt PharmaceuticalsGenentechAstraZenecaNovartis Pharmaceuticals CorporationBiogenGlaxoSmithKline
KeywordsHealth careEquity (law)Health equityMedicaidEthnic groupSocial determinants of healthPublic relationsMedicineMedical educationPsychologyNursingPolitical sciencePublic health

Abstract

fetched live from OpenAlex

OBJECTIVE: We conducted formative research aimed at identifying solutions that address inequitable health outcomes in lupus due to adverse social determinants of health (SDoH). METHODS: We conducted a search for keywords, which provided insights into potential solutions and initiatives underway. An advisory panel of lupus experts iteratively reviewed the list of literature-scoped solutions in working sessions, filling knowledge gaps, which allowed for further defining and classifying solutions based on area of focus, feasibility, and impact. Seven-in-depth semistructured discussions and a modified Delphi survey approach were leveraged to align the advisory panel based on feasibility, impact, and costs of the proposed solutions. RESULTS: Thirty-three solutions were identified and classified into four key categories: financial safety net, patient education and shared decision-making, physician education, and other solutions. High-impact solutions that were prioritized included the following: "collecting granular information like patient-reported outcomes to provide personalized care and accelerate development of new products," "expanding Medicaid coverage via infrastructure," and "supporting people living with lupus in applying and getting approval for disability." CONCLUSION: Addressing health and health care disparities linked to negative SDoH is a key goal in the management of lupus, as disparities in outcomes can be stark. Increasing the visibility of potential solutions and aligning the community on top priorities can enable more efficient and effective contributions to health care equity and ultimately better health outcomes for people living with lupus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.331
metaresearch head score (Gemma)0.249
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.331
Threshold uncertainty score0.825

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3310.249
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0030.005
Bibliometrics0.0210.009
Science and technology studies0.0100.009
Scholarly communication0.0150.015
Open science0.0080.028
Research integrity0.0090.008
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.131
GPT teacher head0.458
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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