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Record W4413638083 · doi:10.1007/s00586-025-09282-1

Bipolar spinal correction reduces transfusion rate and hospital stay compared with traditional posterior spinal fusion in children with scoliosis secondary to cerebral palsy

2025· article· en· W4413638083 on OpenAlexaff
Kristopher Lundine, Matthias Z. H. Lu, Timothy C. Borden, Samuel Yoon, Michael Johnson

Bibliographic record

VenueEuropean Spine Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicScoliosis diagnosis and treatment
Canadian institutionsSunnybrook Health Science Centre
Fundersnot available
KeywordsMedicineCerebral palsyNeurosurgeryScoliosisSpinal fusionAnesthesiaSurgeryPhysical medicine and rehabilitation

Abstract

fetched live from OpenAlex

PURPOSE: Patients with neuromuscular scoliosis due to Cerebral Palsy (CP) are complex due to their curve severity and associated medical comorbidities. Spinal fusion is associated with high risk of peri-operative complications and large blood loss requiring allogenic red blood cell (RBC) transfusion. In June 2017, our tertiary paediatric institution implemented a new minimally-invasive approach for the treatment of neuromuscular scoliosis, Bipolar Spinal Correction (Bipolar), a technique first published by Miladi et al. in 2018. This study represents an analysis of the initial experience of this technique to see if it achieves the goal of minimally invasive surgery by decreasing surgical stress in this high-risk population. METHODS: We identified patients with an underlying diagnosis of CP who underwent primary single-day surgical correction for their scoliosis between 2010 and 2024 at a single paediatric institution. Patients either underwent a primary posterior spinal fusion (PSF) or Bipolar surgeries. Revision procedures and patients undergoing anterior spinal surgery were excluded. Patient charts and x-rays were reviewed to collect data on demographics, pre-operative curve severity and peri-operative details. RESULTS: PSF cohort included 46 patients and Bipolar included 78 patients. Demographic and curve severity data were similar between the groups. Bipolar surgery resulted in shorter operative times than PSF (228 min vs. 270 min) and reduced blood loss based on cell-saver return (113 mL vs. 382 mL) and lowest post-operative Hgb level (99.8 g/L vs. 89.6 g/L). Allogenic RBC transfusion rate was markedly reduced in the Bipolar cohort compared to the PSF cohort both intra-operatively (2.6% vs. 23.9%) and post-operatively (14.1% vs. 23.9%). No patient in the Bipolar cohort required mass transfusion protocol, defined as needing more than 3 units of allogenic RBC, compared with 2 patients in the PSF cohort. Post-operative hospital length-of-stay was reduced in the Bipolar cohort compared to PSF (6.5 days vs. 8 days). CONCLUSIONS: When compared with traditional posterior spinal fusion, Bipolar Spinal Correction resulted in decreased operative times, less surgical blood loss, decreased allogenic transfusion rate, and reduced post-operative hospital length of stay in the treatment of children with CP and scoliosis. LEVEL OF EVIDENCE: Level III, Retrospective Comparative Cohort.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.054
Threshold uncertainty score0.928

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.248
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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