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Record W4413683239 · doi:10.1016/j.hpb.2025.08.004

Prospective, randomized, controlled clinical study on single-incision laparoscopic cholecystectomy: an analysis of 449 cases from a single center

2025· article· en· W4413683239 on OpenAlexaboutno aff
Xiang Pan, Liufan Zha, Huanbing Zhu, Jinhong Wu, Zhiquan Chen, Chao Li, Dan Ye, Daren Liu

Bibliographic record

VenueHPB · 2025
Typearticle
Languageen
FieldMedicine
TopicMinimally Invasive Surgical Techniques
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineSingle CenterCholecystectomyLaparoscopic cholecystectomySurgeryRandomized controlled trialGeneral surgery

Abstract

fetched live from OpenAlex

BACKGROUND: Single-incision laparoscopic cholecystectomy (SILC), a minimally invasive alternative to conventional laparoscopic cholecystectomy (CLC), may improve postoperative recovery and cosmetic outcomes but faces concerns about complications and technical demands. This randomized controlled trial compares SILC and CLC using conventional laparoscopic instruments. MATERIALS AND METHODS: 891 patients were randomized to SILC (n = 449) or CLC (n = 442). Operative parameters, postoperative recovery, complications, and patient-reported outcomes were evaluated. Primary endpoints were operative time, blood loss, and complication rates. Secondary outcomes included hospital stay, pain scores, and cosmetic satisfaction (Vancouver scar scores). RESULTS: SILC showed similar operative time (55.11 ± 22.88 vs 51.81 ± 23.61 min, p = 0.907) and blood loss (10.89 ± 26.37 vs 10.14 ± 14.38 ml, p = 0.475) versus CLC. SILC patients had shorter hospitalization (1.94 ± 1.87 vs 2.25 ± 2.49 days, p < 0.001), lower pain scores (2.19 ± 0.88 vs 2.80 ± 0.75, p = 0.016), and better scar outcomes (2.41 ± 1.81 vs 3.54 ± 1.61, p = 0.020). Complication rates like bile leakage and hernias were marginally higher in SILC but not statistically significant. CONCLUSION: SILC is a safe, effective alternative to CLC, offering better postoperative recovery and cosmetic results. However, patient selection and surgical expertise are crucial to optimize outcomes and minimize complications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.009
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.002
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.390
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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