Anesthetic Protocol For Patients With Hereditary Hemorrhagic Telangiectasia Undergoing Enteroscopy For Angiodysplastic Lesions: A Case Report
Bibliographic record
Abstract
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is a rare genetic disorder that poses significant perioperative challenges due to the risk of bleeding. We report the case of a 47-year-old male with HHT undergoing double-balloon enteroscopy (DBE) for gastrointestinal angiodysplastic lesions. Preoperative preparation included detailed screening for anemia, coagulation status, and arteriovenous malformations (AVMs). Anesthetic considerations included airway management strategies to prevent and detect telangiectasia rupture, maintenance of hemodynamic stability, and post-procedural bleeding management. Intraoperative measures included careful intubation, hemodynamic monitoring, and mitigation of embolic risks. The procedure was completed successfully, managing over 100 lesions without incident. This case highlights the importance of personalized perioperative protocols, intraoperative vigilance, and post-operative care which are crucial for the successful management of patients with HHT. We present our HHT-specific anesthetic protocol from a hematology center to address the unique challenges of HHT in endoscopic clinics, contributing to safer outcomes for patients with this rare genetic disorder.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".