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Record W4413739922 · doi:10.71117/jnnp.2024.1104

Cognitive Impairment of Temporal Lobe Epilepsy and Risk Factors

2024· article· en· W4413739922 on OpenAlexaboutno aff
Ulziizaya Sodov

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsnot available
FundersNational Center for Mental HealthMongolian National University of Medical Sciences
KeywordsEpilepsyTemporal lobeCognitive impairmentCognitionPsychologyNeuroscienceCognitive psychologyMedicine

Abstract

fetched live from OpenAlex

Introduction: Focal epilepsy accounts for 60% of all clinical epilepsy cases, while temporal lobe epilepsy (TLE) accounts for 40%.Cognitive impairment such as language, attention, executive function, and memory impairment are common in temporal lobe epilepsy, and researchers believe that seizure frequency and duration can cause severe hippocampal sclerosis, as well as a secondary impact on neuronal metabolism and structure, which leads to cognitive impairment.Aim: The goal is to determine the cognitive impairment of temporal lobe epilepsy, the clinical characteristics and risk factors. Materials and Methods:A cross-sectional study of 50 adults with temporal lobe epilepsy from the National Center for Mental Health used a questionnaire and Montreal Cognitive Assessment (MoCA).Results: We included 50 adults aged 26 to 61 with temporal lobe epilepsy, 52% of respondents were male, 48% were female, with an average age of 43.78±8.20 years.The study found that 92% of individuals showed cognitive impairment, with mean MoCA scores of 17.50±4.57.Long lasting seizure is a high-risk factor for cognitive function, with statistical significance (p=0.03).Seizure onset age was linked with increased attention impairments and poor visuospatial function (p=0.005), while higher seizure frequency was associated with decreased calculation (p=0.04),language (p=0.009), and drawing skills (p=0.013).Conclusion: Our study found that 58% of respondents showed moderate cognitive impairment.Low education level, earlier age of seizure onset, high seizure frequency, extended seizure duration, presence of aura, and refractory temporal lobe epilepsy all have a statistically significant effect on cognitive impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.289
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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