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Record W4413753575 · doi:10.1016/j.cag.2025.104394

SHREC 2025: Protein surface shape retrieval including electrostatic potential

2025· preprint· en· W4413753575 on OpenAlexafffund
Taher Yacoub, Camille Depenveiller, Atsushi Tatsuma, Tin Barisin, Eugen Rusakov, Udo Göbel, Yuxu Peng, Yuki Kagaya, Joon Hong Park, Daisuke Kihara, Marco Guerra, Andrea Ranieri, Ulderico Fugacci, Silvia Biasotti, Ruiwen He, Halim Benhabiles, Adnane Cabani, Karim Hammoudi, Haotian Li, Hao Huang, Chunyan Li, Alireza Tehrani, Fanwang Meng, Farnaz Heidar‐Zadeh, Matthieu Montès

Bibliographic record

VenueComputers & Graphics · 2025
Typepreprint
Languageen
FieldMaterials Science
TopicEnzyme Structure and Function
Canadian institutionsQueen's University
FundersSchool of Graduate Studies, Queen's UniversityMinistry of Science and Technology, TaiwanEuropean Research Executive AgencyMinistero dell'Istruzione e del MeritoNatural Sciences and Engineering Research Council of CanadaQueen's UniversityEuropean CommissionAgence Nationale de la RechercheNational Institutes of HealthNational Science Foundation
KeywordsSurface (topology)Computer scienceSurface proteinBiophysicsChemistryBiological systemGeometryMathematicsBiology

Abstract

fetched live from OpenAlex

This SHREC 2025 track dedicated to protein surface shape retrieval involved 9 participating teams. We evaluated the performance in retrieval of 15 proposed methods on a large dataset of 11,555 protein surfaces with calculated electrostatic potential (a key molecular surface descriptor). The performance in retrieval of the proposed methods was evaluated through different metrics (Accuracy, Balanced accuracy, F1 score, Precision and Recall). The best retrieval performance was achieved by the proposed methods that used the electrostatic potential complementary to molecular surface shape. This observation was also valid for classes with limited data which highlights the importance of taking into account additional molecular surface descriptors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.029
Threshold uncertainty score0.097

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.007
Meta-epidemiology (narrow)0.0040.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0040.003
Science and technology studies0.0010.001
Scholarly communication0.0040.004
Open science0.0050.004
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0290.034

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.268
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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