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Record W4413800016 · doi:10.21037/tp-2025-102

The efficacy and safety of robotic, laparoscopic, and open surgery for pediatric choledochal cysts: a systematic review and network meta-analysis

2025· review· en· W4413800016 on OpenAlexaboutno aff
Hongbin Cui, Xing Wang, W. Frank An, Mali Chen, Xingxia Zhang

Bibliographic record

VenueTranslational Pediatrics · 2025
Typereview
Languageen
FieldMedicine
TopicPediatric Hepatobiliary Diseases and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCholedochal cystsMeta-analysisGeneral surgeryOpen surgerySurgeryInternal medicine

Abstract

fetched live from OpenAlex

Background: Pediatric choledochal cysts (CCs) are typically managed via surgical treatment, and a growing number of pediatric patients with CC are undergoing robotic surgery. However, whether it offers superior safety and efficacy compared to open surgery and laparoscopic surgery remains unclear. The primary aim of this study was to compare the efficacy and safety of three surgical approaches [open cyst excision with a Roux-en-Y hepaticojejunostomy (OP), laparoscopic cyst excision with a Roux-en-Y hepaticojejunostomy (LA), and robotic cyst excision with a Roux-en-Y hepaticojejunostomy (RO)] for CC in children. Methods: PubMed, Embase, Cochrane Library, and Web of Science databases were systematically searched. Two independent reviewers assessed the studies for eligibility and quality and then extracted the relevant data. Confidence in Network Meta-Analysis (CINeMA) and the Newcastle-Ottawa Scale (NOS) were applied for assessing quality. Direct statistical analyses were carried out via Stata 14.0 (StataCorp), while a network meta-analysis was performed through use of using ADDIS 1.16.18 (GetReal Initiative, Innovative Medicines Initiative). Results: A total of 18 studies were included for analysis. OP had the significantly shortest operative time; RO had the significantly shortest hospital stay; and LA had the significantly lowest incidence of postoperative bowel obstruction. Conclusions: RO is effective and safe for the management of CC. The opportunity to convert to open surgery should not be missed due to fears of excessive bleeding or increased postoperative bile leakage.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.947
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0090.002
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.373
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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